Pheochromocytoma (PCC) is a type of neuroendocrine tumor that originates from adrenal
medulla or extra-adrenal chromaffin cells and results in the production of catecholamine …

Colorectal cancer (CRC) stands as the third most prevalent ailment globally and represents
the primary cause of mortality associated with cancer. Significant advancements have been …

Idiopathic pulmonary fibrosis (IPF) is an irreversible and life-threatening lung disease of
unknown etiology presenting only a few treatment options. TGF-β signaling orchestrates a …

Aberrant activation of the NLRP3 inflammasome is recognized to induce a chronic
inflammatory response in the liver, ultimately leading to hepatic fibrosis. HSP90 is suggested …

Liver cancer stands as the fourth leading global cause of death, and its prognosis remains
grim due to the limited effectiveness of current medical interventions. Among the various …

Hypoxia-inducible factor-1 (HIF-1) is a key regulator for balancing oxygen in the cells. It is a
transcription factor that regulates the expression of target genes involved in oxygen …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Liver cirrhosis,
hepatitis B, hepatitis C, and non-alcoholic fatty liver disease represent major risk factors of …

Thyroid cancer is the most common endocrine malignancy, affecting nearly 600,000 new
patients worldwide. Treatment with the BRAF inhibitor sorafenib partially prolongs …

Hepatic fibrosis arising from chronic liver injury is characterized by dysregulated healing,
including hepatic stellate cell activation and excessive deposition of extracellular matrix …

Beta‐blockers are commonly used medications that antagonize β‐adrenoceptors, reducing
sympathetic nervous system activity. Emerging evidence suggests that beta‐blockers may …