A combined spectroscopic and quantum chemical approach to study the molecular interaction between anti-inflammatory drug Hydrocortisone and amino acid L …

J Saikia, TG Devi, T Karlo - Journal of Molecular Structure, 2023 - Elsevier
The work presented in the manuscript addresses the molecular interaction of Hydrocortisone
with l-Phenylalanine accomplished by density functional theory (B3LYP/6–311 G (d, p)), and …

Preparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals

A Karakucuk, S Tort - Pharmaceutical Development and …, 2020 - Taylor & Francis
The objective of this study was to develop resveratrol nanocrystals to solve low water
solubility issues of resveratrol and adsorb them to the polycaprolactone nanofibers …

Microfluidic mixing and devices for preparing nanoparticulate drug delivery systems

Y Zhang, D Liu, H Zhang, HA Santos - Microfluidics for Pharmaceutical …, 2019 - Elsevier
Nanotechnology-based therapeutics, operating at scales of billionths of a meter, hold great
potentials in altering the methods and efficiency of drug delivery. However, a major …

[HTML][HTML] Utilization of the Drug–Polymer Solid Dispersion Obtained by Ball Milling as a Taste Masking Method in the Development of Orodispersible Minitablets with …

M Trofimiuk, K Olechno, E Trofimiuk… - Pharmaceutics, 2024 - mdpi.com
The objective of the conducted research was to design 2 mm orodispersible minitablets of
pediatric doses of hydrocortisone (0.5 mg; 1.0 mg) with desirable pharmaceutical properties …

[PDF][PDF] Enhanced dissolution rate of Ketoprofen by fabricating into smart nanocrystals.

J Khan, S Bashir, MA Khan, R Ghaffar… - Pakistan Journal of …, 2019 - researchgate.net
The low bioavailability of Ketoprofen is associated with its hydrophobic nature that can be
solved by nanonization. For this purpose, a polymeric solution with drug concentration of …

Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

K Sugita, N Takata, E Yonemochi - Pharmaceutics, 2022 - mdpi.com
We evaluated the in vitro permeability of nanoparticle formulations of high and low lipophilic
compounds under non-sink conditions, wherein compounds are not completely dissolved …

[PDF][PDF] Smart nanocrystal of indomethacin: Nanonization and characterization through top down method of media milling.

J Khan, S Bashir, MA Khan, A Naz… - Pakistan Journal of …, 2020 - researchgate.net
Indomethacin is potent and effective drug belongs to NSAID group having low
bioavailability. To address this issue the novel method is Nanosuspensions which can be …

[PDF][PDF] 難水溶性化合物のNon-Sink 条件下における膜透過性機構に関する研究

杉田和也, すぎたかずや - stella.repo.nii.ac.jp
医薬品開発においては, より高い薬効の実現と適応疾患領域の広範囲化が重要な課題である.
この課題を解決するために, 近年, 医薬品候補化合物の分子構造はより複雑化 …