Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species

K Nie, K Ma, W Luo, Z Shen, Z Yang, M Xiao… - Frontiers in cellular …, 2021 - frontiersin.org
Roseburia intestinalis is an anaerobic, Gram-positive, slightly curved rod-shaped flagellated
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …

Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer

N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …

Understanding the role of the gut microbiome in gastrointestinal cancer: A review

D Ağagündüz, E Cocozza, Ö Cemali… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

Influence of the gut microbiome, diet, and environment on risk of colorectal cancer

M Song, AT Chan, J Sun - Gastroenterology, 2020 - Elsevier
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

The intestinal microbiota in colorectal cancer

H Tilg, TE Adolph, RR Gerner, AR Moschen - Cancer cell, 2018 - cell.com
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …

Gut bacteria composition drives primary resistance to cancer immunotherapy in renal cell carcinoma patients

L Derosa, B Routy, M Fidelle, V Iebba, L Alla, E Pasolli… - European urology, 2020 - Elsevier
Background The development of immune checkpoint blockade (ICB) has revolutionized the
clinical outcome of renal cell carcinoma (RCC). Nevertheless, improvement of durability and …

[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential

E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …

The oral microbiota in colorectal cancer is distinctive and predictive

B Flemer, RD Warren, MP Barrett, K Cisek, A Das… - Gut, 2018 - gut.bmj.com
Background and aims Microbiota alterations are linked with colorectal cancer (CRC) and
notably higher abundance of putative oral bacteria on colonic tumours. However, it is not …