Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

N-linked glycosylation is a post-translational modification crucial for membrane protein
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …

Clear cell renal cell carcinomas (ccRCCs) represent∼ 75% of RCC cases and account for
most RCC-associated deaths. Inter-and intratumoral heterogeneity (ITH) results in varying …

Aberrant glycosylation plays a fundamental role in key pathological steps of tumour
development and progression. Glycans have roles in cancer cell signalling, tumour cell …

Fluorescence-guided photodynamic therapy (PDT) has been considered as an emerging
strategy for precise cancer treatment by making use of photosensitizers (PSs) with reactive …

Association of aberrant glycosylation with melanoma progression is based mainly on
analyses of cell lines. Here we present a systems-based study of glycomic changes and …

Prostate cancer (PCa) is a leading cause of cancer death for males in western countries.
The current gold standard for PCa diagnosis-template needle biopsies-often does not …

BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …

Many gene products exhibit great structural heterogeneity because of an array of
modifications. These modifications are not directly encoded in the genomic template but …

Glycans–simple or complex carbohydrates–play key roles as recognition determinants and
modulators of numerous physiological and pathological processes. Thus, many …