The catalytic asymmetric aldol reaction

TD Machajewski, CH Wong - … Chemie International Edition, 2000 - Wiley Online Library
The construction of C− C bonds with complete control of the stereochemical course of a
reaction is of utmost importance for organic synthesis. The aldol reaction—the simple …

Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies

KM Koeller, CH Wong - Chemical Reviews, 2000 - ACS Publications
Identifying the functional roles of carbohydrates in biological systems has been an area of
intense study in recent years. Although carbohydrates were once viewed only as inert …

Recent advances in the chemoenzymatic synthesis of carbohydrates and carbohydrate mimetics

HJM Gijsen, L Qiao, W Fitz, CH Wong - Chemical reviews, 1996 - ACS Publications
The aldol condensation has been an effective method in organic synthesis for the formation
of carboncarbon bonds. 1 Much effort has been directed toward making these reactions …

C− C bond-forming lyases in organic synthesis

M Brovetto, D Gamenara, P Saenz Mendez… - Chemical …, 2011 - ACS Publications
Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …

[图书][B] Preparative carbohydrate chemistry

S Hanessian - 1997 - taylorfrancis.com
Detailing commonly used methods and procedures, this reference discusses the reactions
and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the …

Enzymes in organic synthesis: application to the problems of carbohydrate recognition (part 1)

CH Wong, RL Halcomb, Y Ichikawa… - … International Edition in …, 1995 - Wiley Online Library
Carbohydrates on cell surfaces are information molecules. Although only seven or eight
monosaccharides are commonly used as building blocks in mammalian systems, the …

Biocatalytic Methods for C C Bond Formation

K Fesko, M Gruber‐Khadjawi - ChemCatChem, 2013 - Wiley Online Library
Carbon‐carbon bond formation is among the most challenging transformations in the
organic synthetic chemistry. Enzymes capable to perform this reaction are of great interest …

Die katalysierte asymmetrische Aldolreaktion

TD Machajewski, CH Wong - Angewandte Chemie, 2000 - Wiley Online Library
Die Knüpfung von C‐C‐Bindungen unter vollständiger Kontrolle des stereochemischen
Verlaufs einer Reaktion ist in der organischen Synthesechemie von großer Bedeutung. Die …

Enzymatic CC bond formation in asymmetric synthesis

WD Fessner, C Walter - Bioorganic Chemistry: Models and Applications, 2005 - Springer
Catalytic aldol reactions are among the most useful synthetic methods with a high potential
for convergent asymmetric synthesis. As an increasing number of lyases is becoming …

Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies

KM Koeller, CH Wong - Glycobiology, 2000 - academic.oup.com
The ultimate goal in complex carbohydrate synthesis is to develop synthetic tools which are
simple and easily accessible to glycobiologists. This review will describe methods which …