Effectiveness of azithromycin mass drug administration on trachoma: a systematic review

T Xiong, Y Yue, WX Li, I Choonara, S Qazi… - Chinese medical …, 2021 - mednexus.org
Backgrounds: Azithromycin mass drug administration (MDA) is a key part of the strategy for
controlling trachoma. This systematic review aimed to comprehensively summarize the …

Changes in trachoma indicators in Kiribati with two rounds of azithromycin mass drug administration, measured in serial population-based surveys

EB Goodhew, R Taoaba… - PLOS Neglected …, 2023 - journals.plos.org
Baseline mapping in the two major population centers of Kiribati showed that trachoma was
a public health problem in need of programmatic interventions. After conducting two annual …

Validation of immunoassays for the Chlamydia trachomatis antigen Pgp3 using a chimeric monoclonal antibody

B Goodhew, X Tang, J Goldstein, J Lee, D Martin… - Scientific Reports, 2023 - nature.com
Seroepidemiology, or measuring antibodies to pathogens to estimate population-level
exposure, can provide useful public health data. The tests used, however, often lack …

Serological responses to trachoma antigens prior to the start of mass drug administration: Results from population-based baseline surveys, North Darfur, Sudan

AM Sanders, BE Elshafie, Z Abdalla… - … American journal of …, 2024 - pmc.ncbi.nlm.nih.gov
After years of programmatic inaccessibility, in 2019–2020 the Sudan Federal Ministry of
Health Trachoma Control Program conducted population-based trachoma surveys in three …

Serology, infection, and clinical trachoma as tools in prevalence surveys for re-emergence of trachoma in a formerly hyperendemic district

M Odonkor, F Naufal, B Munoz, H Mkocha… - PLoS neglected …, 2021 - journals.plos.org
Background To eliminate trachoma as a public health problem, countries must achieve a
district-level prevalence of trachomatous inflammation—follicular (TF)< 5% in children ages …

Risk of seroconversion and seroreversion of antibodies to Chlamydia trachomatis pgp3 in a longitudinal cohort of children in a low trachoma prevalence district in …

X Chen, B Munoz, H Mkocha, CA Gaydos… - PLoS neglected …, 2022 - journals.plos.org
Background Serologic testing for chlamydial antibodies is one potential tool for trachoma
monitoring. Understanding the dynamics of seroconversion and seroreversion in low …

Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase …

E Paulet, V Contreras, M Galhaut… - PLOS Neglected …, 2024 - journals.plos.org
Background Trachoma is a leading cause of infection-related blindness worldwide. This
disease is caused by recurrent Chlamydia trachomatis (Ct) infections of the conjunctiva and …

Prevalence and associated factors of active trachoma among 1–9 years of age children in Andabet district, northwest Ethiopia, 2023: A multi-level mixed-effect …

ZA Asmare, BL Seifu, KU Mare… - PLOS Neglected …, 2023 - journals.plos.org
Background Trachoma is the chief cause of preventable blindness worldwide and has been
earmarked for elimination as a public health problem by 2030. Despite the five-year Surgery …

[HTML][HTML] Prevalence of ocular Chlamydia trachomatis infection in Amhara region, Ethiopia, after 8 years of trachoma control interventions

SD Nash, A Chernet, P Weiss, AW Nute… - The American Journal …, 2023 - ncbi.nlm.nih.gov
Although trachoma mass drug administration (MDA) programs target ocular Chlamydia
trachomatis, the global trachoma control program does not monitor infection as a measure of …

Wait and watch: A trachoma surveillance strategy from Amhara region, Ethiopia

E Sata, F Seife, Z Ayele, SA Murray… - PLOS Neglected …, 2024 - journals.plos.org
Background Trachoma recrudescence after elimination as a public health problem has been
reached is a concern for control programs globally. Programs typically conduct district-level …