Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age
and has become increasingly more common with advances in age. The number of …

Malaria is a significant public health problem in more than 100 countries and causes an
estimated 200 million new infections every year. Despite the significant effort to eradicate …

Tumor necrosis factor alpha (TNFα) is the most widely studied pleiotropic cytokine of the
TNF superfamily. In pathophysiological conditions, generation of TNFα at high levels leads …

Background—Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis and
increased cardiovascular morbidity and mortality. Striking similarities exist in the …

OBJECTIVES: Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with
an increased prevalence of coronary heart disease and a high cardiovascular (CV) mortality …

BACKGROUND: Psychologic stress modifies immune function and cytokine production.
OBJECTIVE: We examined relationships between caregiver stress on the following markers …

Evidence linking psychological stress to the expression of asthma and atopy continues to
grow. Examining the underlying molecular mechanisms linking stress to asthma and other …

Increased oxidative stress is believed to be one of the mechanisms responsible for
hyperglycemia-induced tissue damage and diabetic complications. In these studies, we …

Thymic stromal lymphopoietin (TSLP) is a novel cytokine that triggers dendritic cell-mediated
T helper (Th)-2 inflammatory responses. Previous studies have demonstrated that human …

Sepsis is a syndrome precipitated by immune dysregulation in response to infection, and
represents a pivotal factor in global mortality attributed to diseases. The recent consensus …