HLA matching provides numerous benefits in organ transplantation including better graft
function, fewer rejection episodes, longer graft survival, and the possibility of reduced …

The number of kidney transplant recipients returning to dialysis after graft failure is steadily
increasing over time. Patients with a failed kidney transplant have been shown to have a …

The angiotensin II type 1 receptor (AT1R) is an emerging target of functional non‐HLA
antibodies (Ab). We examined the potential of determining the degree of presensitization …

Background. Kidney transplant recipients are at high risk of opportunistic infection. The aims
of this study were to describe the epidemiology, clinical features and prognosis of …

Background. Long-term success of renal transplantation depends upon the quality of the
donor organ, avoidance of peritransplant and early posttransplant damage (rejection), and …

Despite considerable advances in immunosuppression and in short-term graft survival, little
improvement has been observed in long-term survival rates. About 30% of patients lose their …

Calcineurin inhibitor (CNI) withdrawal has been used as a strategy to improve renal allograft
function, however, it also carries risk of acute rejection. We conducted a systematic review of …

Allorecognition is the activation of the adaptive immune system to foreign human leukocyte
antigen (HLA) resulting in the generation of alloantibodies. Due to a high polymorphism …

An increasing number of patients waitlisted for kidney transplantation have a previously
failed graft. Retransplantation provides a significant improvement in morbidity, mortality, and …

Background: Failed kidney transplant recipients benefit from a new graft as the general
incident dialysis population, although additional challenges in the management of these …