Currently, static cold storage (SCS) of hearts from donations after brainstem death remains
the standard clinically. However, machine perfusion (MP) is considered an approach for …

Cardiac transplantation has become limited by a critical shortage of suitable organs from
brain-dead donors. Reports describing the successful clinical transplantation of hearts …

To extend the preservation of donor hearts beyond the current 4–6 h, this paper explores
heart cryopreservation by vitrification—cryogenic storage in a glass‐like state. While organ …

Background. Heart transplantation (HTx) is, at present, the most effective therapy for end-
stage heart failure patients; however, the number of patients on the waiting list is rising …

Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …

Ex vivo heart perfusion (EVHP) may facilitate resuscitation of discarded donor hearts and
expand the donor pool; however, a reliable means of demonstrating organ viability prior to …

Cardiac transplantation is the gold standard for treatment for select patients with end-stage
heart failure, yet donor supply is limited. Ex vivo machine perfusion is an emerging …

Clinically, both percutaneous and surgical approaches to deliver viral vectors to the heart
either have resulted in therapeutically inadequate levels of transgene expression or have …

DCD heart transplantation is feasible with excellent early outcomes. In the face of continued
and significant donor organ shortage and inevitable wait list attrition, the rejection of suitable …

This article summarizes recent knowledge and clinical advances in machine perfusion (MP)
of thoracic organs. MP of thoracic organs has gained much attention during the last decade …