The role of anthocyanins as antidiabetic agents: From molecular mechanisms to in vivo and human studies

F Les, G Cásedas, C Gómez, C Moliner… - Journal of Physiology …, 2021 - Springer
Diabetes mellitus is a chronic metabolic disease characterized by high blood glucose
concentration. Nowadays, type 2 diabetes or insulin resistant diabetes is the most common …

Natural antioxidant polyphenols on inflammation management: Anti-glycation activity vs metalloproteinases inhibition

L Crascì, MR Lauro, G Puglisi… - Critical reviews in food …, 2018 - Taylor & Francis
The diet polyphenols are a secondary metabolites of plants able to act on inflammation
process. Their anti-inflammatory activity is articulated through several mechanisms that are …

[HTML][HTML] Natural products as a source of inspiration for novel inhibitors of advanced glycation endproducts (AGEs) formation

S Velichkova, K Foubert, L Pieters - Planta medica, 2021 - thieme-connect.com
Protein glycation, a post-translational modification found in biological systems, is often
associated with a core defect in glucose metabolism. In particular, advanced glycation …

Cyanidin-3-rutinoside acts as a natural inhibitor of intestinal lipid digestion and absorption

T Thilavech, S Adisakwattana - BMC complementary and alternative …, 2019 - Springer
Abstract Background Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin,
possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties …

A new italian purple corn variety (Moradyn) byproduct extract: antiglycative and hypoglycemic in vitro activities and preliminary bioaccessibility studies

L Ferron, R Colombo, B Mannucci, A Papetti - Molecules, 2020 - mdpi.com
The reuse of byproducts from agricultural and food industries represents the key factor in a
circular economy, whose interest has grown in the last two decades. Thus, the extraction of …

[HTML][HTML] Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma

C Macedo, PC Costa, F Rodrigues - Food Research International, 2024 - Elsevier
In recent years, there has been a significant demand for natural products as a mean of
disease prevention or as an alternative to conventional medications. The driving force for …

Exploring inhibitory effect and mechanism of hesperetin-Cu (II) complex against protein glycation

X Peng, X Hu, K Liu, D Gong, G Zhang - Food Chemistry, 2023 - Elsevier
Inhibition of advanced glycation end products (AGEs) formed in protein glycosylation is
crucial for minimizing diabetic complications. Herein, the anti-glycation potential of …

[HTML][HTML] Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line

SS Ferreira, MR Domingues, C Barros, SAO Santos… - Food chemistry: X, 2022 - Elsevier
The accumulation of advanced glycation end-products (AGEs) in the body is implicated in
numerous diseases, being methylglyoxal (MGO) one of the main precursors. One of the …

Inhibitory effect of epicatechin gallate on protein glycation

X Wu, G Zhang, X Hu, J Pan, Y Liao, H Ding - Food Research International, 2019 - Elsevier
Protein glycation can produce the advanced glycation end products (AGEs), which has a
potential health risk due to its relevance with diabetic complications. Searching for potent …

Black mulberry fruit extract alleviates streptozotocin-induced diabetic nephropathy in rats: targeting TNF-α inflammatory pathway

TK Abouzed, KM Sadek, EW Ghazy… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives This study was designed to investigate the effect of Morus nigra fruit extract in
retarding the progression of diabetic nephropathy in streptozotocin (STZ)-induced diabetic …