Metagenomic tools in microbial ecology research
Ability to directly sequence DNA from the environment permanently changed microbial
ecology. Here, we review the new insights to microbial life gleaned from the applications of …
ecology. Here, we review the new insights to microbial life gleaned from the applications of …
Long-read sequencing in deciphering human genetics to a greater depth
Through four decades' development, DNA sequencing has inched into the era of single-
molecule sequencing (SMS), or the third-generation sequencing (TGS), as represented by …
molecule sequencing (SMS), or the third-generation sequencing (TGS), as represented by …
Nanopore sequencing of RNA and cDNA molecules in Escherichia coli
High-throughput sequencing dramatically changed our view of transcriptome architectures
and allowed for ground-breaking discoveries in RNA biology. Recently, sequencing of full …
and allowed for ground-breaking discoveries in RNA biology. Recently, sequencing of full …
Toward kingdom-wide analyses of gene expression
Gene expression data for Archaeplastida are accumulating exponentially, with more than
300 000 RNA-sequencing (RNA-seq) experiments available for hundreds of species. The …
300 000 RNA-sequencing (RNA-seq) experiments available for hundreds of species. The …
Long-read sequencing reveals oncogenic mechanism of HPV-human fusion transcripts in cervical cancer
M Liu, Z Han, Y Zhi, Y Ruan, G Cao, G Wang, X Xu… - Translational …, 2023 - Elsevier
Integration of high-risk human papillomavirus (HPV) into the host genome is a crucial event
for the development of cervical cancer, however, the underlying mechanism of HPV …
for the development of cervical cancer, however, the underlying mechanism of HPV …
New insights for biosensing: Lessons from microbial defense systems
Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …
millions of years. Such defense systems can protect them from being attacked by invading …
Systematic characterization of non‐coding RNAs in triple‐negative breast cancer
J Mei, L Hao, H Wang, R Xu, Y Liu, Y Zhu… - Cell …, 2020 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is one of the most aggressive subtypes of breast
cancer with negativity for oestrogen receptor (ER), progesterone receptor (PR) and human …
cancer with negativity for oestrogen receptor (ER), progesterone receptor (PR) and human …
Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection
N Nguyen Quang, S Goudey, E Ségéral, A Mohammad… - Retrovirology, 2020 - Springer
Background Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-
1) replication that is tightly regulated both temporally and spatially. More than 50 different …
1) replication that is tightly regulated both temporally and spatially. More than 50 different …
Challenges in identifying mRNA transcript starts and ends from long-read sequencing data
Long-read sequencing (LRS) technologies have the potential to revolutionize scientific
discoveries in RNA biology through the comprehensive identification and quantification of …
discoveries in RNA biology through the comprehensive identification and quantification of …
Physiological Characteristic Changes and Full-Length Transcriptome of Rose (Rosa chinensis) Roots and Leaves in Response to Drought Stress
W Li, L Fu, Z Geng, X Zhao, Q Liu… - Plant and Cell …, 2020 - academic.oup.com
Rose (Rosa chinensis) is the most important ornamental crops worldwide. However, the
physiological and molecular mechanism of rose under drought stress remains elusive. In …
physiological and molecular mechanism of rose under drought stress remains elusive. In …