Despite considerable advances in treatment approaches in the past two decades, multiple myeloma remains an incurable disease. Treatments for myeloma continue to evolve with …
JK Jasielec, T Kubicki, N Raje, R Vij… - Blood, The Journal …, 2020 - ashpublications.org
In this phase 2 multicenter study, we evaluated the incorporation of autologous stem cell transplantation (ASCT) into a carfilzomib-lenalidomide-dexamethasone (KRd) regimen for …
M Offidani, L Corvatta, S Morè, D Nappi… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy is changing the paradigm of multiple myeloma (MM) management and daratumumab is the first-in-class human monoclonal antibody targeting CD38 approved for …
Survival in multiple myeloma has improved greatly during the past 2 decades, but this change has primarily benefited patients who have standard-risk disease. Patients with high …
K Maclachlan, B Diamond, F Maura… - Best Practice & …, 2020 - Elsevier
The changing landscape of treatment options for multiple myeloma has led to a higher proportion of patients achieving deep, long-lasting responses to therapy. With the …
C Charalampous, T Kourelis - Frontiers in Oncology, 2022 - frontiersin.org
Multiple Myeloma (MM), the second most common hematologic malignancy, has been the target of many therapeutic advances over the past two decades. The introduction of novel …
Multiple Myeloma, the second most prevalent hematologic malignancy, yet lacks an established curative therapy. However, overall response rate to modern four-drug regimens …
D Kazandjian, CC Mo, O Landgren… - British journal of …, 2020 - Wiley Online Library
Recent advances in multiple myeloma include numerous approvals of novel therapies with unprecedented efficacy, a rapid and sustained tempo of new drug development, and further …
R Mina, S Oliva, M Boccadoro - Journal of clinical medicine, 2020 - mdpi.com
Minimal residual disease (MRD) detection represents a sensitive tool to appropriately measure the response obtained with therapies for multiple myeloma (MM). The achievement …