Several pyrazole‐thiazole hybrids featuring two potentially bioactive pharmacophores with
or without linker have been synthesized using the molecular hybridization approach as …

Abstract Prangos uechtritzii Boiss & Hausskn stands out for its rich bioactive constituents
including prantschimgin (PRA), imperatorin (IMP), suberosin (SUB), adicardin (ADI), and …

In this study, a series of derivatives of pyrazole hybrid structures containing carbonitrile and
substituted thiazole moiety were designed to search for selective COX‐2 inhibition. The …

Objective: The first goal of the present study is to investigate the role of mitochondria due to
the Crabtree effect in HepG2 cells exposed to ISO in either glucose-or galactose …

Heterocyclic compounds that include nitrogen and their derivatives have long been
regarded as excellent sources of medicinal substances. Pyrazole is a compound with two …

Aim: This study aims to evaluate the alterations in Oxypeucedanin (OXY)-mediated
anticancer activity in different media. Second aim is to predict the affinity of OXY to electron …

In this presented study, a series of new carbonitrile‐substituted pyrazole‐tosyl amide
derivatives were designed and synthesized according to previous studies. The …

In this study, a series of derivatives of pyrazole hybrid structures containing carbonitrile and
substituted thiazole moiety were designed to search for selective COX-2 inhibition. The …

Objective: The first goal of the present study is to investigate the role of mitochondria due to
the Crabtree effect in HepG2 cells exposed to ISO in either glucose-or galactose …

Objective: This study includes the investigation of the antimicrobial potential of a series of
compounds designed by hybridization of thiazole, hydrazone and pyrazole systems …