Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models

E Taoufik, G Kouroupi, O Zygogianni… - Open …, 2018 - royalsocietypublishing.org
Synaptic dysfunction in CNS disorders is the outcome of perturbations in physiological
synapse structure and function, and can be either the cause or the consequence in specific …

Making sense of patient-derived iPSCs, transdifferentiated neurons, olfactory neuronal cells, and cerebral organoids as models for psychiatric disorders

J Unterholzner, V Millischer, C Wotawa… - International Journal …, 2021 - academic.oup.com
The improvement of experimental models for disorders requires a constant approximation
towards the dysregulated tissue. In psychiatry, where an impairment of neuronal structure …

Genetics of aggression in Alzheimer's disease (AD)

WJ Lukiw, EI Rogaev - Frontiers in aging neuroscience, 2017 - frontiersin.org
Alzheimer's disease (AD) is a terminal, age-related neurological syndrome exhibiting
progressive cognitive and memory decline, however AD patients in addition exhibit ancillary …

[PDF][PDF] Neurologie, Neurochirurgie und Psychiatrie

R Zellen - kup.at
Differenzierte somatische Zellen des Menschen können zu pluripotenten Stammzellen
reprogrammiert werden. Diese induzierten pluripotenten Stammzellen können dann wieder …

[PDF][PDF] Reprogrammierte Zellen: Zukunft der psychiatrischen Forschung?//Reprogrammed cells: future of psychiatric research?

U Sauerzopf, A Weidenauer… - Journal für …, 2017 - scholar.archive.org
Differenzierte somatische Zellen des Menschen können zu pluripotenten Stammzellen
reprogrammiert werden. Diese induzierten pluripotenten Stammzellen können dann wieder …