We carried out systematic review and meta-analysis to evaluate whether peripheral levels of
pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor …

Objective Inflammation plays a crucial role in the pathogenesis of mild cognitive impairment
(MCI) and Alzheimer's disease (AD). Our study aimed to analyse previous inconsistent …

Objectives Increasing evidence suggests that inflammation is involved in Alzheimer's
disease (AD) pathology. This study quantitatively summarised the data on peripheral …

Vascular contribution to cognitive impairment and dementia (VCID) is a clinical label
encompassing a wide range of cognitive disorders progressing from mild to major vascular …

Amyloid-β plaques and neurofibrillary tangles are the main neuropathological hallmarks in
Alzheimer's disease (AD), the most common cause of dementia in the elderly. However, it …

Background The development of mild cognitive impairment (MCI) and Alzheimer's disease
(AD) may be associated with an inflammatory process. Inflammatory cytokines may be a …

Background Increasing evidence suggests an association between pro-inflammatory diets
and cognitive function. However, only a few studies based on small sample sizes have …

Being isolated from the peripheral system by the blood–brain barrier, the brain has long
been considered a completely impervious tissue. However, recent findings show that the gut …

Background Neuroinflammation has been recognized as a feature of Alzheimer's disease
(AD), and mild cognitive impairment (MCI) is believed to share several pathological features …

In recent years, the pharmaceutical business has seen a considerable increase in data
digitization. With digitization, however, comes the challenge of obtaining, analyzing, and …