Mechanochemical principles of spatial and temporal patterns in cells and tissues

A Bailles, EW Gehrels, T Lecuit - Annual review of cell and …, 2022 - annualreviews.org
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Light-sheet microscopy and its potential for understanding developmental processes

Y Wan, K McDole, PJ Keller - Annual review of cell and …, 2019 - annualreviews.org
The ability to visualize and quantitatively measure dynamic biological processes in vivo and
at high spatiotemporal resolution is of fundamental importance to experimental …

Symmetry, thermodynamics, and topology in active matter

MJ Bowick, N Fakhri, MC Marchetti, S Ramaswamy - Physical Review X, 2022 - APS
The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Getting around the cell: physical transport in the intracellular world

SS Mogre, AI Brown, EF Koslover - Physical Biology, 2020 - iopscience.iop.org
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

[HTML][HTML] Self-organized nuclear positioning synchronizes the cell cycle in Drosophila embryos

VE Deneke, A Puliafito, D Krueger, AV Narla… - Cell, 2019 - cell.com
The synchronous cleavage divisions of early embryogenesis require coordination of the cell-
cycle oscillator, the dynamics of the cytoskeleton, and the cytoplasm. Yet, it remains unclear …

Guiding self-organized pattern formation in cell polarity establishment

P Gross, KV Kumar, NW Goehring, JS Bois, C Hoege… - Nature Physics, 2019 - nature.com
Spontaneous pattern formation in Turing systems relies on feedback. But patterns in cells
and tissues seldom form spontaneously—instead they are controlled by regulatory …

The relative densities of cytoplasm and nuclear compartments are robust against strong perturbation

K Kim, J Guck - Biophysical journal, 2020 - cell.com
The cell nucleus is a compartment in which essential processes such as gene transcription
and DNA replication occur. Although the large amount of chromatin confined in the finite …

A hierarchy of protein patterns robustly decodes cell shape information

MC Wigbers, TH Tan, F Brauns, J Liu, SZ Swartz… - Nature Physics, 2021 - nature.com
Many cellular processes, such as cell division,–, cell motility, wound healing and tissue
folding,, rely on the precise positioning of proteins on the membrane. Such protein patterns …

Three-dimensional chiral morphodynamics of chemomechanical active shells

S Yin, B Li, XQ Feng - … of the National Academy of Sciences, 2022 - National Acad Sciences
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …

Establishment of the vertebrate body plan: Rethinking gastrulation through stem cell models of early embryogenesis

B Steventon, L Busby, AM Arias - Developmental Cell, 2021 - cell.com
A striking property of vertebrate embryos is the emergence of a conserved body plan across
a wide range of organisms through the process of gastrulation. As the body plan unfolds …