Ten decadal advances in fungal biology leading towards human well-being

A Mapook, KD Hyde, K Hassan, BM Kemkuignou… - Fungal Diversity, 2022 - Springer
Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

On top of biosynthetic gene clusters: How epigenetic machinery influences secondary metabolism in fungi

BT Pfannenstiel, NP Keller - Biotechnology advances, 2019 - Elsevier
Fungi produce an abundance of bioactive secondary metabolites which can be utilized as
antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are …

Histone modification dynamics at H3K27 are associated with altered transcription of in planta induced genes in Magnaporthe oryzae

W Zhang, J Huang, DE Cook - PLoS genetics, 2021 - journals.plos.org
Transcriptional dynamic in response to environmental and developmental cues are
fundamental to biology, yet many mechanistic aspects are poorly understood. One such …

Comparative “Omics” of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis

EM Niehaus, M Münsterkötter… - Genome Biology and …, 2016 - academic.oup.com
Species of the Fusarium fujikuroi species complex (FFC) cause a wide spectrum of often
devastating diseases on diverse agricultural crops, including coffee, fig, mango, maize, rice …

Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds

L Zhang, OE Fasoyin, I Molnár, Y Xu - Natural Product Reports, 2020 - pubs.rsc.org
Covering: 2014 up to the third quarter of 2019 Entomopathogens constitute a unique,
specialized trophic subgroup of fungi, most of whose members belong to the order …

Conserved responses in a war of small molecules between a plant-pathogenic bacterium and fungi

JE Spraker, P Wiemann, JA Baccile, N Venkatesh… - MBio, 2018 - Am Soc Microbiol
Small-molecule signaling is one major mode of communication within the polymicrobial
consortium of soil and rhizosphere. While microbial secondary metabolite (SM) production …

Chromatin-dependent regulation of secondary metabolite biosynthesis in fungi: is the picture complete?

J Collemare, MF Seidl - FEMS microbiology reviews, 2019 - academic.oup.com
Fungal secondary metabolites are small molecules that exhibit diverse biological activities
exploited in medicine, industry and agriculture. Their biosynthesis is governed by co …

Comparative genomics of geographically distant Fusarium fujikuroi isolates revealed two distinct pathotypes correlating with secondary metabolite profiles

EM Niehaus, HK Kim, M Münsterkötter… - PLoS …, 2017 - journals.plos.org
Fusarium fujikuroi causes bakanae (“foolish seedling”) disease of rice which is
characterized by hyper-elongation of seedlings resulting from production of gibberellic acids …

[HTML][HTML] Virulence factors of the genus Fusarium with targets in plants

A Gutiérrez-Sánchez, J Plasencia… - Microbiological …, 2023 - Elsevier
Fusarium spp. comprise various species of filamentous fungi that cause severe diseases in
plant crops of both agricultural and forestry interest. These plant pathogens produce a wide …

How to completely squeeze a fungus—advanced genome mining tools for novel bioactive substances

A Schüller, L Studt-Reinhold, J Strauss - Pharmaceutics, 2022 - mdpi.com
Fungal species have the capability of producing an overwhelming diversity of bioactive
substances that can have beneficial but also detrimental effects on human health. These so …