[HTML][HTML] Polyomaviruses and human cancer: molecular mechanisms underlying patterns of tumorigenesis
MK White, K Khalili - Virology, 2004 - Elsevier
Polyomaviruses are DNA tumor viruses with small circular genomes encoding only six
proteins including three structural capsid proteins. Despite this simplicity, our understanding …
proteins including three structural capsid proteins. Despite this simplicity, our understanding …
Human polyomaviruses and brain tumors
Polyomaviruses are DNA tumor viruses with small circular genomes. Three polyomaviruses
have captured attention with regard to their potential role in the development of human brain …
have captured attention with regard to their potential role in the development of human brain …
Incidence of BK virus and JC virus viruria in human immunodeficiency virus-infected and-uninfected subjects
RB Markowitz, HC Thompson, JF Mueller… - Journal of Infectious …, 1993 - academic.oup.com
Abstract BK virus (BKV) and JC virus (JCV) are present within the renal system of most
adults. Reactivation may be linked to immunodeficiency, since many of the extant virus …
adults. Reactivation may be linked to immunodeficiency, since many of the extant virus …
Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells
M Safak, R Barrucco, A Darbinyan, Y Okada… - Journal of …, 2001 - Am Soc Microbiol
In addition to encoding the structural and regulatory proteins, many viruses encode auxiliary
proteins, some of which have been shown to play important roles in lytic and latent states of …
proteins, some of which have been shown to play important roles in lytic and latent states of …
The polyomavirus, JCV, and its involvement in human disease
K Khalili, J Gordon, MK White - Polyomaviruses and human diseases, 2006 - Springer
The human neurotropic polyomavirus, JC virus (JCV), is the etiologic agent of progressive
multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous …
multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous …
Transcriptional regulation of human JC polyomavirus promoters by cellular proteins YB-1 and Pur alpha in glial cells
NN Chen, K Khalili - Journal of virology, 1995 - Am Soc Microbiol
Transcription of the human polyomavirus (JCV) genome is regulated by host cell proteins
and the viral early protein, T antigen. A region called the lytic control element (LCE), located …
and the viral early protein, T antigen. A region called the lytic control element (LCE), located …
Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control …
NN Chen, CF Chang, GL Gallia… - Proceedings of the …, 1995 - National Acad Sciences
Human JC polyomavirus (JCV) is the etiologic agent of the neurodegenerative disease
progressive mulifocal leukoencephalopathy. By using JCV as a model, we investigated the …
progressive mulifocal leukoencephalopathy. By using JCV as a model, we investigated the …
The molecular biology of JC virus, causative agent of progressive multifocal leukoencephalopathy
RJ Frisque, FA White III - Molecular Neurovirology: Pathogenesis of Viral …, 1992 - Springer
The rare demyelinating brain disease, progressive multifocal leukoencephalopathy (PML),
was first described by Åström and coworkers (1) in 1958, and a viral etiology was suggested …
was first described by Åström and coworkers (1) in 1958, and a viral etiology was suggested …
Transcriptional regulation of human polyomavirus JC: evidence for a functional interaction between RelA (p65) and the Y-box-binding protein, YB-1
GV Raj, M Safak, GH MacDonald, K Khalili - Journal of virology, 1996 - Am Soc Microbiol
The transcriptional control region of the human neurotropic polyomavirus JC virus contains a
consensus NF-kappa B site which has been shown to enhance both basal and extracellular …
consensus NF-kappa B site which has been shown to enhance both basal and extracellular …
Reciprocal Interaction between Two Cellular Proteins, Purα and YB-1, Modulates Transcriptional Activity of JCVCY in Glial Cells
M Safak, GL Gallia, K Khalili - Molecular and cellular biology, 1999 - Taylor & Francis
Cross communication between regulatory proteins is an important event in the control of
eukaryotic gene transcription. Here we have examined the structural and functional …
eukaryotic gene transcription. Here we have examined the structural and functional …