In the past decade, single-cell technologies have proliferated and improved from their
technically challenging beginnings to become common laboratory methods capable of …

Spatial omics technologies enable a deeper understanding of cellular organizations and
interactions within a tissue of interest. These assays can identify specific compartments or …

The diverse cell types of an organ have a highly structured organization to enable their
efficient and correct function. To fully appreciate gene functions in a given cell type, one …

Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …

A hallmark of meiosis is chromosomal pairing, which requires telomere tethering and
rotation on the nuclear envelope through microtubules, driving chromosome homology …

Motile cilia are hair-like cell extensions that beat periodically to generate fluid flow along
various epithelial tissues within the body. In dense multiciliated carpets, cilia were shown to …

Neurogenesis is significantly reduced in Alzheimer's disease (AD) and is a potential
therapeutic target. Contrary to humans, a zebrafish can regenerate its diseased brain, and …

Dysfunction of motile cilia in ependymal cells has been proposed to be a pathogenic cause
of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in …

Choroid plexuses (ChPs) produce cerebrospinal fluid and sense non-cell-autonomous
stimuli to control the homeostasis of the central nervous system. They are mainly composed …

High-resolution maps of embryonic development suggest that acquisition of cell identity is
not limited to canonical germ layers but proceeds via alternative routes. Despite evidence …