[HTML][HTML] Ki67 is a promising molecular target in the diagnosis of cancer
LT Li, G Jiang, Q Chen… - Molecular …, 2015 - build.spandidos-publications.com
The expression of Ki67 is strongly associated with tumor cell proliferation and growth, and is
widely used in routine pathological investigation as a proliferation marker. The nuclear …
widely used in routine pathological investigation as a proliferation marker. The nuclear …
Ki-67 as a prognostic biomarker in invasive breast cancer
Simple Summary In breast cancer development, the expression of Ki-67 is strongly
associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki …
associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki …
Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis
To metastasize, carcinoma cells must attenuate cell–cell adhesion to disseminate into
distant organs. A group of transcription factors, including Twist1, Snail1, Snail2, ZEB1, and …
distant organs. A group of transcription factors, including Twist1, Snail1, Snail2, ZEB1, and …
ORegAnno 3.0: a community-driven resource for curated regulatory annotation
Abstract The Open Regulatory Annotation database (ORegAnno) is a resource for curated
regulatory annotation. It contains information about regulatory regions, transcription factor …
regulatory annotation. It contains information about regulatory regions, transcription factor …
KDEL receptors are differentially regulated to maintain the ER proteome under calcium deficiency
Retention of critical endoplasmic reticulum (ER) luminal proteins needed to carry out diverse
functions (eg, protein synthesis and folding, lipid metabolism) is mediated through a carboxy …
functions (eg, protein synthesis and folding, lipid metabolism) is mediated through a carboxy …
ConTra v3: a tool to identify transcription factor binding sites across species, update 2017
Transcription factors are important gene regulators with distinctive roles in development, cell
signaling and cell cycling, and they have been associated with many diseases. The ConTra …
signaling and cell cycling, and they have been associated with many diseases. The ConTra …
Mechanisms and evolution of control logic in prokaryotic transcriptional regulation
SAFT van Hijum, MH Medema… - … and Molecular Biology …, 2009 - Am Soc Microbiol
SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …
their ability to fine-tune gene expression to adequately respond to internal and external …
Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma
JM Wu, Y Xu, NJ Skill, H Sheng, Z Zhao, M Yu… - Molecular cancer, 2010 - Springer
Background Autotaxin (ATX) is an extracellular lysophospholipase D that generates
lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Both ATX and LPA have …
lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Both ATX and LPA have …
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis
M Reichert, S Takano, J Von Burstin… - Genes & …, 2013 - genesdev.cshlp.org
Pancreatic exocrine cell plasticity can be observed during development, pancreatitis with
subsequent regeneration, and also transformation. For example, acinar–ductal metaplasia …
subsequent regeneration, and also transformation. For example, acinar–ductal metaplasia …
IKKα controls canonical TGFβ–SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells
M Brandl, B Seidler, F Haller, J Adamski… - Journal of cell …, 2010 - journals.biologists.com
The epithelial to mesenchymal transition (EMT) is a crucial step in tumor progression, and
the TGFβ–SMAD signaling pathway is an inductor of EMT in many tumor types. One …
the TGFβ–SMAD signaling pathway is an inductor of EMT in many tumor types. One …