Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Mesoporous silica nanoparticles for drug delivery: Current insights

M Vallet-Regí, M Colilla, I Izquierdo-Barba, M Manzano - Molecules, 2017 - mdpi.com
This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug
delivery systems. Their intrinsic structural, textural and chemical features permit to design …

Applications of surface modification technologies in nanomedicine for deep tumor penetration

Z Li, X Shan, Z Chen, N Gao, W Zeng… - Advanced …, 2021 - Wiley Online Library
The impermeable barrier of solid tumors due to the complexity of their components limits the
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …

Sol–gel‐based advanced porous silica materials for biomedical applications

Q Lei, J Guo, A Noureddine, A Wang… - Advanced Functional …, 2020 - Wiley Online Library
Porous silica‐based materials have burgeoning applications ranging from fillers and
additives, to adsorbents, catalysts, and recently therapeutic agents and vaccines in …

Nanomaterials as promising alternative in the infection treatment

M Vallet-Regí, B González… - International journal of …, 2019 - mdpi.com
Both the prevalence of antibiotic resistance and the increased biofilm-associated infections
are boosting the demand for new advanced and more effective treatment for such infections …

[HTML][HTML] Our contributions to applications of mesoporous silica nanoparticles

M Vallet-Regí - Acta Biomaterialia, 2022 - Elsevier
Our contribution to mesoporous silica materials in the field of biomedicine are reported in
this article. This perspective article represents our work in the basics of the material …

Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: An update

RR Castillo, D Lozano, B González… - Expert opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction Mesoporous silica nanoparticles (MSNs) are outstanding
nanoplatforms for drug delivery. Herein, the most recent advances to turn MSN-based …

Future of Mesoporous Silica Nanoparticles in Nanomedicine: Protocol for Reproducible Synthesis, Characterization, Lipid Coating, and Loading of Therapeutics …

A Noureddine, A Maestas-Olguin, L Tang… - 2023 - ACS Publications
Owing to their uniform and tunable particle size, pore size, and shape, along with their
modular surface chemistry and biocompatibility, mesoporous silica nanoparticles (MSNs) …

Mesoporous silica nanoparticles for the treatment of complex bone diseases: Bone cancer, bone infection and osteoporosis

M Gisbert-Garzarán, M Manzano, M Vallet-Regí - Pharmaceutics, 2020 - mdpi.com
Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major
issue for modern societies as a consequence of their progressive ageing. Even though …

Nanoparticles to knockdown osteoporosis-related gene and promote osteogenic marker expression for osteoporosis treatment

P Mora-Raimundo, D Lozano, M Manzano… - ACS …, 2019 - ACS Publications
Osteoporosis is the most common disease involving bone degeneration. Current clinical
treatments are not able to offer a satisfying curative effect, so the development of effective …