Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Tracking the immune microenvironment of tumours is essential for understanding the
mechanisms behind the effectiveness of cancer immunotherapies. Molecular imaging of …

In conventional positron emission tomography (PET), only one radiotracer can be imaged at
a time, because all PET isotopes produce the same two 511 keV annihilation photons. Here …

Immunotherapy is currently the most rapidly advancing area of clinical oncology, and
provides the unprecedented opportunity to effectively treat, and even cure, several …

T cells play a determining role in the immunomodulation and prognostic evaluation of
cancer treatments relying on immune activation. While specific biomarkers determine the …

Cancer immunotherapy using immune-checkpoint blockade (ICB) has created a paradigm
shift in the treatment of advanced-stage cancers. The promising antitumour activity of …

Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …

Clinical trials with immune checkpoint inhibitors have provided important insights into the
mode of action of anticancer immune therapies and potential mechanisms of immune …

While chemotherapy delivery by nanocarriers has modestly improved the survival prospects
of pancreatic ductal adenocarcinoma (PDAC), additional engagement of the immune …