The collective activity of a population of neurons, beyond the properties of individual cells, is
crucial for many brain functions. A fundamental question is how activity correlations between …

Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …

The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …

When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

Efficient retrograde access to projection neurons for the delivery of sensors and effectors
constitutes an important and enabling capability for neural circuit dissection. Such an …

Persistent and ramping neural activity in the frontal cortex anticipates specific movements,,,,–
. Preparatory activity is distributed across several brain regions,, but it is unclear which brain …

Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown
how the two structures organize into functional networks to mediate specific behaviors. Here …

Persistent neural activity maintains information that connects past and future events. Models
of persistent activity often invoke reverberations within local cortical circuits, but long-range …

Neural activity and behavior are both notoriously variable, with responses differing widely
between repeated presentation of identical stimuli or trials. Recent results in humans and …