APC is a tumor suppressor gene that exerts its effect through the regulation of the Wnt
signaling pathway. Loss of function mutations of the gene are associated with familial …

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral
cavity and, more generally, the soft and hard tissues of the head and neck as primary or …

Introduction and importance: Complex odontomas are hamartomas representing a
conglomeration of all dental tissues. When developed, they rarely become giant and even …

Background Supernumerary teeth are considered one of the commonly observed dental
anomalies in children. Several theories have been proposed to explain the presence of …

Gardner syndrome is a hereditary disease in which patients develop gastrointestinal polyps,
osteomas, desmoid tumors, epidermoid cysts, fibromas, lipomas, and retinal lesions. Dental …

Background/purpose Idiopathic osteosclerosis (IO) is an intraosseous lesion of
asymptomatic, non-expansive, radiopaque. The study aimed to investigate the prevalence …

Gardner syndrome (GS) is a rare autosomal dominant disorder that can present with
craniomaxillofacial abnormalities. The identification of osteomas or craniomaxillofacial …

The association between genetic syndromes and odontogenic tumors encompasses several
entities, reflecting the intricate interplay between genetic factors and the development of …

Objective This paper reports the first published case of a prehistoric human with five or more
supernumerary teeth. Such cases are often neglected in paleopathology, in part due to a …

Gardner syndrome (GS) is a specific form of familial adenomatous polyposis (FAP), which
manifests as colorectal polyps, multiple osteomas and soft tissue tumors, and in the oral …