Human cytomegalovirus (HCMV) is a ubiquitous human pathogen that can cause severe
disease in immunocompromised individuals, transplant recipients, and to the developing …

Coding mutations in the Leucine-rich repeat kinase 2 (LRRK2) gene, which are associated
with dominantly inherited Parkinson's disease (PD), lead to an increased activity of the …

Beta-herpesvirus infection completely reorganizes the membrane system of the cell. This
system is maintained by the spatiotemporal arrangement of more than 3000 cellular proteins …

Liver sinusoidal endothelial cells (LSEC) are scavenger cells with a remarkably high
capacity for clearance of several blood-borne macromolecules and nanoparticles, including …

Introduction Cytomegaloviruses (CMVs) extensively reorganize the membrane system of the
cell and establish a new structure as large as the cell nucleus called the assembly …

Secondary envelopment of the human cytomegalovirus (HCMV) is a critical but not well-
understood process that takes place at the cytoplasmic viral assembly complex (cVAC) …

The efficiency of virus internalization into target cells is a major determinant of infectivity.
SARS-CoV-2 internalization occurs via S-protein-mediated cell binding followed either by …

Introduction Cytomegalovirus (CMV) infection reorganizes early endosomes (EE), recycling
endosome (RE), and trans-Golgi network (TGN) and expands their intermediates into a large …

Cytomegaloviruses (CMV) cause productive, persistent or latent infections in their hosts.
Productive infection requires the establishment of a complete manufacturing chain in the …

Shortly after entering the cells, cytomegaloviruses (CMVs) initiate massive reorganization of
cellular endocytic and secretory pathways, which results in the forming of the cytoplasmic …