Epidemiological evidence indicates that regular physical activity and/or frequent structured
exercise reduces the incidence of many chronic diseases in older age, including …

Immunotherapy is proving to be an effective therapeutic approach in a variety of cancers. But
despite the clinical success of antibodies against the immune regulators CTLA4 and PD …

Despite decades of surveillance and pharmaceutical and non-pharmaceutical interventions,
seasonal influenza viruses continue to cause epidemics around the world each year. The …

Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon …

Ag/Ag@ AgCl/ZnO hybrid nanostructures are embedded in a hydrogel by a simple two-step
technique. The Ag/Ag@ AgCl nanostructures are assembled in the hydrogel via ultraviolet …

Melatonin is a ubiquitous molecule in nature, being locally synthesized in several cells and
tissues, besides being a hormone that is centrally produced in the pineal gland of …

Circadian rhythms are a ubiquitous feature of virtually all living organisms, regulating a wide
diversity of physiological systems. It has long been established that the circadian clockwork …

Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

The human immune system is highly variable between individuals but relatively stable over
time within a given person. Recent conceptual and technological advances have enabled …

Abstract Circadian (∼ 24-hour) timing systems pervade all kingdoms of life and temporally
optimize behavior and physiology in humans. Relatively recent changes to our …