Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

H Zhao, J Zhang, X Cheng, X Nie, B He - Journal of Ovarian Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
chronic ovulation dysfunction and overabundance of androgens; it affects 6–20% of women …

The Role of NLRP3 Inflammasome in Obesity and PCOS—A Systematic Review and Meta-Analysis

SA Alenezi, R Khan, L Snell, S Aboeldalyl… - International Journal of …, 2023 - mdpi.com
Inflammasomes have recently been implicated in the pathogenesis of several chronic
inflammatory disorders, such as diabetes and obesity. The aim of this meta-analysis was to …

Selenium nanoparticles modulate steroidogenesis-related genes and improve ovarian functions via regulating androgen receptors expression in polycystic ovary …

ABE Abdallah, MA El-Ghannam, AA Hasan… - … Trace Element Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) occurs during the reproductive period in women and is
characterized by reproductive, endocrine, and metabolic disorders. Androgen plays a …

Diacerein attenuate LPS-induced acute lung injury via inhibiting ER stress and apoptosis: Impact on the crosstalk between SphK1/S1P, TLR4/NFκB/STAT3, and …

NS Youssef, AS Elzaitony, NAA Baky - Life Sciences, 2022 - Elsevier
Aims Acute lung injury (ALI) is a life-threatening clinical problem with high mortality rate and
limited treatments or preventive options that represents a major challenge for clinicians …

Transcriptomic screening to identify hub genes and drug signatures for PCOS based on RNA-Seq data in granulosa cells

M Zanjirband, M Baharlooie, Z Safaeinejad… - Computers in Biology …, 2023 - Elsevier
Background Polycystic ovary syndrome (PCOS) is one of the most incident reproductive
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …

Kelulut honey ameliorates oestrus cycle, hormonal profiles, and oxidative stress in letrozole-induced polycystic ovary syndrome rats

DAM Kamal, SF Ibrahim, A Ugusman, MH Mokhtar - Antioxidants, 2022 - mdpi.com
Kelulut honey (KH) has been proven to have excellent antioxidative and anti-inflammatory
properties with unique physicochemical characteristics. Therefore, we investigated the …

Regulation of Insulin Resistance, Lipid Profile and Glucose Metabolism Associated with Polycystic Ovary Syndrome by Tinospora cordifolia

R Rani, HR Chitme, N Kukreti, P Pant… - Nutrients, 2023 - mdpi.com
Background: The plant Tinospora cordifolia (TC), traditionally known as guduchi or giloy, is
used for a number of health conditions as a nutritional supplement and rejuvenation …

Effects of kelulut honey on oestrus cycle regulation and histomorphological changes in letrozole-induced polycystic ovary syndrome rats: a preliminary study

DAM Kamal, SF Ibrahim, A Ugusman, MH Mokhtar - Life, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex reproductive, metabolic, and endocrine
disorder that affects women of reproductive age. Kelulut honey is stingless bee honey that …

High Fat Diet Exaggerate Metabolic and Reproductive PCOS Features by Promoting Oxidative Stress: An Improved EV Model in Rats

D Rakic, J Joksimovic Jovic, V Jakovljevic, V Zivkovic… - Medicina, 2023 - mdpi.com
Background and Objectives: Polycystic ovary syndrome (PCOS) is a frequent multifactorial
endocrinopathy affecting women in the reproductive period, often associated with infertility …

[HTML][HTML] Protective effect of astaxanthin and metformin in the liver of rats in which the polycystic ovary syndrome model was formed by giving letrozole

TT Bal, N Akaras, Ö Demir, RA Ugan - Iranian Journal of Basic …, 2023 - ncbi.nlm.nih.gov
Objective (s): In this study, the effects of astaxanthin on liver tissue in rats with polycystic
ovary syndrome (PCOS) were evaluated. Materials and Methods: Fifty-four Spraque-Dawley …