Editorial neuroAIDS review

P Shapshak, P Kangueane, RK Fujimura, D Commins… - Aids, 2011 - journals.lww.com
NeuroAIDS is a disease that incorporates both infectious and degenerative
pathophysiologic pathways. It has a known cause, has several animal models, and is under …

Impact of alcohol on HIV disease pathogenesis, comorbidities and aging: integrating preclinical and clinical findings

PE Molina, L Simon, AM Amedee… - Alcohol and …, 2018 - academic.oup.com
Alcohol's multisystemic effects impact HIV disease pathogenesis and increase the risk for
comorbidities in persons living with HIV (PLWH). The increased number of aging PLWH …

Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders

AJ Levine, A Quach, DJ Moore, CL Achim… - Journal of …, 2016 - Springer
HIV infection leads to age-related conditions in relatively young persons. HIV-associated
neurocognitive disorders (HAND) are considered among the most prevalent of these …

Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

KW Witwer, AK Watson, JN Blankson, JE Clements - Retrovirology, 2012 - Springer
Background HIV-1-infected elite controllers or suppressors (ES) maintain undetectable viral
loads (< 50 copies/mL) without antiretroviral therapy. The mechanisms of suppression are …

Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers

JP Lopez, LM Fiori, JA Gross, B Labonte… - International Journal …, 2014 - academic.oup.com
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play an important role in
the post-transcriptional regulation of mRNA. These molecules have been the subject of …

Significant effects of antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders

A Borjabad, S Morgello, W Chao, SY Kim… - PLoS …, 2011 - journals.plos.org
Antiretroviral therapy (ART) has reduced morbidity and mortality in HIV-1 infection; however
HIV-1-associated neurocognitive disorders (HAND) persist despite treatment. The reasons …

MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease

SV Yelamanchili, AD Chaudhuri, LN Chen… - Cell death & …, 2010 - nature.com
MicroRNAs (miRNAs) have important roles in regulating a plethora of physiological and
pathophysiogical processes including neurodegeneration. In both human immunodeficiency …

The assessment of selected MiRNAs profile in HIV, HBV, HCV, HIV/HCV, HIV/HBV Co-infection and elite controllers for determination of biomarker

S Yousefpouran, S Mostafaei, PV Manesh… - Microbial …, 2020 - Elsevier
Background The emerging relationship between microRNAs (miRNA) and viral-control is a
topic of interest in the field of HIV. Host-genome might play an important role in the control of …

[HTML][HTML] Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1

AD Chaudhuri, SV Yelamanchili… - The FASEB …, 2013 - ncbi.nlm.nih.gov
Abstract MicroRNA (miR)-142 is up-regulated in the brain in HIV and SIV encephalitis
(SIVE). We identified the cell types where miR-142 is up-regulated and its relevant …

A plasma microRNA signature of acute lentiviral infection: biomarkers of central nervous system disease

KW Witwer, SL Sarbanes, J Liu, JE Clements - Aids, 2011 - journals.lww.com
Objective: Plasma microRNAs (miRNAs) are modulated during disease and are emerging
biomarkers; they have not been characterized in HIV infection. Using our macaque/simian …