Epigenetic mechanisms of inflammasome regulation

G Poli, C Fabi, MM Bellet, C Costantini… - International journal of …, 2020 - mdpi.com
The innate immune system represents the host's first-line defense against pathogens, dead
cells or environmental factors. One of the most important inflammatory pathways is …

Cell-free miRNAs as non-invasive biomarkers in breast cancer: Significance in early diagnosis and metastasis prediction

D Kashyap, H Kaur - Life sciences, 2020 - Elsevier
Breast cancer is one of the genetic diseases causing a high mortality among women around
the world. Despite the availability of advanced diagnostic tools and treatment strategies, the …

Cancer-associated fibroblast-derived exosomal miR-18b promotes breast cancer invasion and metastasis by regulating TCEAL7

Z Yan, Z Sheng, Y Zheng, R Feng, Q Xiao, L Shi… - Cell Death & …, 2021 - nature.com
Studies have shown that cancer-associated fibroblasts (CAFs) play an irreplaceable role in
the occurrence and development of tumors. Therefore, exploring the action and mechanism …

Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/β-catenin signaling

F Ma, J Zhang, L Zhong, L Wang, Y Liu, Y Wang… - Gene, 2014 - Elsevier
MicroRNAs (miRNAs) are strongly implicated in many cancers, including breast cancer.
Recently, microRNA-301a (miR-301a) has been proved to play a substantial role in gastric …

Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials

TK Ng, L Huang, D Cao, YWY Yip, WM Tsang… - Scientific reports, 2015 - nature.com
Cigarette smoking contributes to the development of destructive periodontal diseases and
delays its healing process. Our previous study demonstrated that nicotine, a major …

MicroRNA-mediated epigenetic regulation of inflammasomes in inflammatory responses and immunopathologies

YS Yi - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Inflammation represents the first-line defense mechanism of the host against pathogens and
cellular stress. One of the most critical inflammatory responses is characterized by the …

gga-miRNA-18b-3p Inhibits Intramuscular Adipocytes Differentiation in Chicken by Targeting the ACOT13 Gene

G Sun, F Li, X Ma, J Sun, R Jiang, Y Tian, R Han, G Li… - Cells, 2019 - mdpi.com
Intramuscular fat (IMF) is the most important evaluating indicator of chicken meat quality, the
content of which is positively correlated with tenderness, flavor, and succulence of the meat …

A large-scale analysis of genetic variants within putative miRNA binding sites in prostate cancer

S Stegeman, E Amankwah, K Klein, TA O'Mara, D Kim… - Cancer discovery, 2015 - AACR
Prostate cancer is the second most common malignancy among men worldwide. Genome-
wide association studies have identified 100 risk variants for prostate cancer, which can …

Serum miRNA-27a and miRNA-18b as potential predictive biomarkers of hepatitis C virus-associated hepatocellular carcinoma

NM Rashad, AS El-Shal, SM Shalaby… - Molecular and Cellular …, 2018 - Springer
Hepatitis C virus (HCV) infection remains the main risk factor for chronic hepatitis (CHC),
liver cirrhosis, and hepatocellular carcinoma (HCC). Changes in microRNA (miRNA) profiles …

[HTML][HTML] miR-128 targets the SIRT1/ROS/DR5 pathway to sensitize colorectal cancer to TRAIL-induced apoptosis

B Lian, D Yang, Y Liu, G Shi, J Li, X Yan, K Jin… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an
ideal anti-tumor drug because it exhibits selective cytotoxicity against cancer cells. However …