Heat shock factors (HSFs) are essential for all organisms to survive exposures to acute
stress. They are best known as inducible transcriptional regulators of genes encoding …

The pyridine nucleotides, NAD+ and NADH, are coenzymes that provide oxidoreductive
power for the generation of ATP by mitochondria. In skeletal muscle, exercise perturbs the …

Protein SUMOylation is a critically important posttranslational protein modification that
participates in nearly all aspects of cellular physiology. In the nearly 20 years since its …

Protein modification by SUMO conjugation is an important regulatory event. Sumoylation
usually takes place on a lysine residue embedded in the core consensus motif ψKxE …

SUMOylation is a ubiquitin-related transient posttranslational modification pathway
catalyzing the conjugation of small ubiquitin-like modifier (SUMO) proteins (SUMO1 …

Tissue Engineering of skeletal muscle tissue still remains a major challenge. Every neo‐
tissue construct of clinically relevant dimensions is highly dependent on an intrinsic …

SUMOylation, an essential posttranslational protein modification, is involved in many
eukaryotic cellular signaling pathways. The identification of SUMOylated proteins is difficult …

During the development of multicellular organisms, transcriptional regulation plays an
important role in the control of cell growth, differentiation and morphogenesis. SUMOylation …

Phosphorylation and small ubiquitin-like modifier (SUMO) conjugation contribute to the
spatial and temporal regulation of substrates containing phosphorylation-dependent SUMO …

Sumoylation has recently emerged as a key post-translational modification involved in
many, if not all, biological processes. Small Ubiquitin-like Modifier (SUMO) polypeptides are …