Answer questions and earn CME/CNE The management of squamous cell carcinomas of
the anal canal has evolved from surgery as first‐line treatment to curative chemoradiation …

Purpose Concomitant radiochemotherapy (RCT) is the standard for locally advanced anal
canal carcinoma (LAACC). Questions regarding the role of induction chemotherapy (ICT) …

Anal cancers (AC) are relatively rare tumors. Their incidence is increasing, particularly
among men who have sex with other men due to widespread infection by human papilloma …

Anal squamous cell carcinoma (ASCC) is associated with infection with high-risk strains of
human papilloma virus (HPV) in 70–90% of cases and a rise in incidence has been …

Despite a growing incidence in developed countries and a recent improved understanding
of its pathogenesis, anal cancer management has not evolved over the past decades and …

PURPOSE: The United Kingdom Coordinating Committee on Cancer Research anal cancer
trial demonstrated the benefit of combined modality treatment (CMT) using radiotherapy …

Our aim is to discuss the current established management of care and associated
prevention strategies of anal squamous cell carcinoma (SCCA). In general, the development …

Chemoradiotherapy is the standard-of-care treatment of squamous-cell carcinoma of the
anus (SCCA), and this has not changed in decades. Radiation doses of 50–60 Gy, as used …

Abstract Aim Six Phase III randomized trials have determined the effectiveness of
chemoradiotherapy as primary treatment for anal squamous cell carcinoma (ASCC), but …

Purpose To retrospectively analyze the efficacy of 36 Gy of elective node irradiation and
report patterns of recurrence in patients with anal cancer treated by chemoradiation with the …