In recent years, multidrug-resistant pathogenic microorganisms (MDROs) have emerged as
a severe threat to human health, exhibiting robust resistance to traditional antibiotics. This …

With the growing crisis of antimicrobial resistance, it is critical to continue to seek out new
sources of novel antibiotics. This need has led to renewed interest in natural product …

Antibiotic resistance has emerged as a global threat, rendering the existing conventional
treatment strategies ineffective. In view of this, antimicrobial peptides (AMPs) have proven to …

The proline-rich antimicrobial peptide (PrAMP) drosocin is produced by Drosophila species
to combat bacterial infection. Unlike many PrAMPs, drosocin is O-glycosylated at threonine …

The antimicrobial resistance crisis along with challenges of antimicrobial discovery revealed
the vital necessity to develop new antibiotics. Many of the animal proline-rich antimicrobial …

Abstract The Proline-rich Antimicrobial Peptide (PrAMP) apidaecin (Api) inhibits translation
by binding in the ribosomal nascent peptide exit tunnel, trapping release factors RF1 or RF2 …

Abstract Apidaecin 1b (Api), the first characterized Type II Proline-rich antimicrobial peptide
(PrAMP), is encoded in the honey bee genome. It inhibits bacterial growth by binding in the …

We recently showed that solid-phase peptide synthesis using racemic amino acids yields
stereorandomized peptides comprising all possible diastereomers as homogeneous, single …

Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules
with the potential to combat infections associated with medical implants and biomaterials …

The microbiome includes both 'mutualist'and 'pathogen'microbes, regulated by the same
innate immune architecture. A major question has therefore been: how do hosts prevent …