Epithelial–mesenchymal transition (EMT) is an essential process for morphogenesis and
organ development which reversibly enables polarized epithelial cells to lose their epithelial …

The NCI-60 cancer cell line panel provides a premier model for data integration, and
systems pharmacology being the largest publicly available database of anticancer drug …

Background Advances in the high-throughput omic technologies have made it possible to
profile cells in a large number of ways at the DNA, RNA, protein, chromosomal, functional …

This study was originally conceived to test in a rigorous way the specificity of three major
approaches to high-throughput array-based DNA methylation analysis:(1) MeDIP, or …

The emergence of castrate-resistant prostate cancer (CRPC) contributes to the high mortality
of patients diagnosed with prostate cancer (PCa), which in part could be attributed to the …

Abstract Around 25–40% of cases of hereditary diffuse gastric cancer (HDGC) are caused by
heterozygous E‐cadherin (CDH1) germline mutations. The mechanisms for loss of the …

A common feature shared between several human cancer-associated viruses, such as
Epstein-Barr virus, Hepatitis B virus and Hepatitis C virus, and Human papillomavirus (HPV) …

DNA methylation changes that are recurrent in cancer have generated great interest as
potential biomarkers for the early detection and monitoring of cancer. In such situations …

Abstract The National Cancer Institute's NCI-60 cell line panel, the most extensively
characterized set of cells in existence and a public resource, is frequently used as a …

H3K9 methylation has been linked to a variety of biological processes including position‐
effect variegation, heterochromatin formation and transcriptional regulation. To further …