Prenatal poly (i: C) exposure and other developmental immune activation models in rodent systems

U Meyer - Biological psychiatry, 2014 - Elsevier
It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …

Influence of infection during pregnancy on fetal development

KMA Waldorf, RM McAdams - Reproduction, 2013 - rep.bioscientifica.com
Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

[HTML][HTML] Preterm birth: Inflammation, fetal injury and treatment strategies

AK Boyle, SF Rinaldi, JE Norman, SJ Stock - Journal of reproductive …, 2017 - Elsevier
Preterm birth (PTB) is the leading cause of childhood mortality in children under 5 and
accounts for approximately 11% of births worldwide. Premature babies are at risk of a …

[HTML][HTML] The poly (I: C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

S Reisinger, D Khan, E Kong, A Berger, A Pollak… - Pharmacology & …, 2015 - Elsevier
Increasing epidemiological and experimental evidence implicates gestational infections as
one important factor involved in the pathogenesis of several neuropsychiatric disorders …

The oral microbiome and adverse pregnancy outcomes

CM Cobb, PJ Kelly, KB Williams, S Babbar… - … journal of women's …, 2017 - Taylor & Francis
Significant evidence supports an association between periodontal pathogenic bacteria and
preterm birth and preeclampsia. The virulence properties assigned to specific oral …

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

MS Vermillion, J Lei, Y Shabi, VK Baxter… - Nature …, 2017 - nature.com
Zika virus (ZIKV) crosses the placenta and causes congenital disease. Here we develop an
animal model utilizing direct ZIKV inoculation into the uterine wall of pregnant …

Bacterial aetiological agents of intra-amniotic infections and preterm birth in pregnant women

GL Mendz, NO Kaakoush, JA Quinlivan - Frontiers in cellular and …, 2013 - frontiersin.org
Infection-related preterm birth is a leading cause of infant mortality and morbidity; knowledge
of bacterial populations invading the amniotic cavity and the routes of invasion is required to …

Rodent hypoxia–ischemia models for cerebral palsy research: a systematic review

P Rumajogee, T Bregman, SP Miller, JY Yager… - Frontiers in …, 2016 - frontiersin.org
Cerebral palsy (CP) is a complex multifactorial disorder, affecting approximately 2.5–3/1000
live term births, and up to 22/1000 prematurely born babies. CP results from injury to the …

based surface-enhanced Raman spectroscopy for diagnosing prenatal diseases in women

W Kim, SH Lee, JH Kim, YJ Ahn, YH Kim, JS Yu… - ACS …, 2018 - ACS Publications
We report the development of a surface-enhanced Raman spectroscopy sensor chip by
decorating gold nanoparticles (AuNPs) on ZnO nanorod (ZnO NR) arrays vertically grown on …

SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders

H Dubey, RK Sharma, S Krishnan… - Frontiers in …, 2022 - frontiersin.org
Pregnant women constitute one of the most vulnerable populations to be affected by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the cause of coronavirus …