N-methyl-D-aspartate (NMDA) receptors, a family of L-glutamate receptors, play an
important role in learning and memory, and are critical for spatial memory. These receptors …

Major depressive disorder is a severe and complex mental disorder. Impaired
neurotransmission and disrupted signalling pathways may influence neuroplasticity, which …

Major depressive disorder (MDD) is primarily conceptualized as a mood disorder but
cognitive dysfunction is also prevalent, and may limit the daily function of MDD patients …

Stroke is the most common cause of acquired epilepsy, but treatment for preventing the
development of post-stroke epilepsy is still unavailable. Since stroke results in neuronal …

Tinnitus is one of the most prevalent auditory disorders worldwide, manifesting in both
chronic and acute forms. The pathology of tinnitus has been mechanistically linked to …

Abstract Background Although Amyloid beta (Aβ) and N-methyl d-aspartate receptors
(NMDARs are involved in Ca 2+ neurotoxicity, the function of mitochondrial calcium …

Major depressive disorder (MDD) is a serious and complex mental illness. Currently, many
antidepressants are available in the market for the treatment of MDD. However, these agents …

Activation of the basolateral amygdala can modulate the strength of fear memories,
including those in single-trial inhibitory avoidance (IA) tasks. Memory retention, measured by …

Sevoflurane, a typical inhaled anesthetic, is widely used in patients of all ages during
surgery. The negative effects, such as inducing cell death and damaging spatial memory, of …

Impaired activation of the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) by
D-serine is linked to cognitive aging. Whether this deregulation may be used to initiate …