Erythropoietin Receptor/β common receptor: a shining light on acute kidney injury induced by ischemia-reperfusion

Y Wu, B Yang - Frontiers in immunology, 2021 - frontiersin.org
Acute kidney injury (AKI) is a health problem worldwide, but there is a lack of early
diagnostic biomarkers and target-specific treatments. Ischemia-reperfusion (IR), a major …

Dapagliflozin alleviates renal fibrosis in a mouse model of adenine-induced renal injury by inhibiting TGF-β1/MAPK mediated mitochondrial damage

J Zeng, H Huang, Y Zhang, X Lv, J Cheng… - Frontiers in …, 2023 - frontiersin.org
Renal fibrosis is a common pathological outcome of various chronic kidney diseases, and as
yet, there is no specific treatment. Dapagliflozin has shown renal protection in some clinical …

Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat

H Tang, P Zhang, L Zeng, Y Zhao, L Xie… - Stem Cell Research & …, 2021 - Springer
Background Tubulointerstitial fibrosis (TIF) is one of the main pathological features of
various progressive renal damages and chronic kidney diseases. Mesenchymal stromal …

The potential role of Na-K-ATPase and its signaling in the development of anemia in chronic kidney disease

KD Maxwell, J Chuang, M Chaudhry… - American Journal …, 2021 - journals.physiology.org
Chronic kidney disease (CKD) is one of the most prominent diseases affecting our
population today. According to the Factsheet published by Centers for Disease Control and …

Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence

T Duangchan, M Rattanasompattikul… - Experimental …, 2022 - journals.sagepub.com
Anemia is a major complication in over 50% of chronic kidney disease (CKD) patients. One
of the main causes of anemia in CKD is the reduction of erythropoietin (EPO) synthesis from …

Low hemoglobin levels predict increased radiation‐induced trismus rates in nasopharyngeal cancer

E Somay, B Yilmaz, E Topkan, B Pehlivan… - Oral …, 2024 - Wiley Online Library
Purpose To investigate the predictive significance of hemoglobin (Hb) values in the
incidence of radiation‐induced trismus (RIT) in locally advanced nasopharyngeal carcinoma …

Identification of biomarkers of chronic kidney disease among kidney-derived proteins

K Higashisaka, S Takeya, H Kamada, M Obana… - Clinical Proteomics, 2022 - Springer
Background Chronic kidney disease (CKD) has few objective symptoms, and it is difficult to
make an early diagnosis by using existing methods. Therefore, new biomarkers enabling …

Effects of Etanercept on TNF‐α Inhibition in Rats with Adenine‐Induced Chronic Kidney Disease

E Mendieta-Condado… - BioMed Research …, 2022 - Wiley Online Library
Introduction. Chronic kidney disease (CKD) constitutes a chronic inflammatory state
associated with an increase in inflammatory mediators and profibrotic molecules such as …

Worth of pan-immune-inflammation value in trismus prediction after concurrent chemoradiotherapy for nasopharyngeal carcinomas

E Somay, B Yilmaz, E Topkan… - The International …, 2024 - journals.sagepub.com
Objective Radiation-induced trismus (RIT), one of the rare but serious side effects of
concurrent chemoradiotherapy (C-CRT), is difficult to predict with high accuracy. We aimed …

Erythropoietin enhances iron bioavailability in HepG2 cells by downregulating hepcidin through mTOR, C/EBPα and HIF-1α

RE Maltaneri, ME Chamorro, SE Gionco… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The regulation of iron (Fe) levels is essential to maintain an adequate supply for
erythropoiesis, among other processes, and to avoid possible toxicity. The liver-produced …