Fibrinogen and atherosclerotic cardiovascular diseases—review of the literature and clinical studies

S Surma, M Banach - International Journal of Molecular Sciences, 2021 - mdpi.com
Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease,
cerebrovascular disease, and peripheral arterial disease, represent a significant cause of …

Fibrinogen and fibrin: synthesis, structure, and function in health and disease

AS Wolberg - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Fibrinogen is an extraordinary molecule by any estimation. It is large, structurally intricate,
and circulates at high concentrations. Its biological end product, insoluble fibrin (ogen) or …

Fibrinogen and the risk of thrombosis

P De Moerloose, F Boehlen… - … in thrombosis and …, 2010 - thieme-connect.com
Fibrinogen contributes to thrombosis risk in different ways. Indeed, various mutations in the
fibrinogen genes predispose to thrombosis. At the same time, high levels of fibrinogen are …

Circulating biomarkers for predicting cardiovascular disease risk; a systematic review and comprehensive overview of meta-analyses

TC van Holten, LF Waanders, PG de Groot, J Vissers… - PloS one, 2013 - journals.plos.org
Background Cardiovascular disease is one of the major causes of death worldwide.
Assessing the risk for cardiovascular disease is an important aspect in clinical decision …

Pathophysiology of atherosclerosis: the role of inflammation

D Tousoulis, AM Kampoli… - Current …, 2011 - ingentaconnect.com
Atherosclerosis is a disease of arteries and is characterized by endothelial dysfunction,
vascular inflammation, and the build-up of lipids, cholesterol, calcium, and cellular debris …

Fibrinogen and factor XIII at the intersection of coagulation, fibrinolysis and inflammation

B Hoppe - Thrombosis and haemostasis, 2014 - thieme-connect.com
Fibrinogen and factor XIII are two essential proteins that are involved directly in fibrin gel
formation as the final step of a sequence of reactions triggered by a procoagulant stimulus …

From multi-omics approaches to personalized medicine in myocardial infarction

C Zhan, T Tang, E Wu, Y Zhang, M He, R Wu… - Frontiers in …, 2023 - frontiersin.org
Myocardial infarction (MI) is a prevalent cardiovascular disease characterized by myocardial
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …

Fibrinogen and cardiovascular disease: genetics and biomarkers

D Tousoulis, N Papageorgiou, E Androulakis… - Blood reviews, 2011 - Elsevier
Several prospective epidemiological studies and clinical observations provided evidence
regarding fibrinogen and coronary artery disease (CAD). Many of these studies firmly …

A Mendelian randomization of γ′ and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke

J Maners, D Gill, N Pankratz, MA Laffan… - Blood, The Journal …, 2020 - ashpublications.org
Fibrinogen is a key component of the coagulation cascade, and variation in its circulating
levels may contribute to thrombotic diseases, such as venous thromboembolism (VTE) and …

The role of hs-CRP, D-dimer and fibrinogen in differentiating etiological subtypes of ischemic stroke

LB Liu, M Li, WY Zhuo, YS Zhang, AD Xu - PloS one, 2015 - journals.plos.org
The aim of this study was to evaluate the diagnostic value of the serum biochemical markers
high-sensitivity C-reactive protein (hs-CRP), D-dimer (DD) and fibrinogen (Fg) in …