The cerebral signature for pain perception and its modulation

I Tracey, PW Mantyh - Neuron, 2007 - cell.com
Clinical pain is a serious public health issue. Treatment of pain-related suffering requires
knowledge of how pain signals are initially interpreted and subsequently transmitted and …

Stress-induced hyperalgesia

EM Jennings, BN Okine, M Roche, DP Finn - Progress in neurobiology, 2014 - Elsevier
The importance of the modulation of pain by emotion is now widely recognised. In particular,
stress and anxiety, depending on their nature, duration and intensity, can exert potent, but …

[HTML][HTML] Cannabinoids and the endocannabinoid system in fibromyalgia: A review of preclinical and clinical research

SL Bourke, AK Schlag, SE O'Sullivan, DJ Nutt… - Pharmacology & …, 2022 - Elsevier
Characterised by chronic widespread musculoskeletal pain, generalised hyperalgesia, and
psychological distress, fibromyalgia (FM) is a significant unmet clinical need. The …

Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid

T Schneider, A Roman, A Basta-Kaim, M Kubera… - …, 2008 - Elsevier
Autism is a severe behavioral disorder characterized by pervasive impairments in social
interactions, deficits in verbal and non-verbal communication, and stereotyped behaviors …

Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: issues for a therapeutic approach in autism

T Schneider, J Turczak, R Przewłocki - Neuropsychopharmacology, 2006 - nature.com
Environmental enrichment has been repeatedly shown to affect multiple aspects of brain
function, and is known to improve cognitive, behavioral, and histopathological outcome after …

Animal models of fibromyalgia: What is the best choice?

ES Brum, G Becker, MFP Fialho, SM Oliveira - Pharmacology & …, 2022 - Elsevier
Fibromyalgia (FM) is a complex syndrome, with an indefinite aetiology and intricate
pathophysiology that affects 2–3% of the world population. From the beginning of the 2000s …

[PDF][PDF] Stress-induced hyperalgesia: animal models and putative mechanisms

H Imbe, Y Iwai-Liao, E Senba - Front Biosci, 2006 - article.imrpress.com
Introduction 3. Stress potentiates a nociceptive response in humans 4. Animal models and
putative mechanisms of hyperalgesia 4.1. Acute stress-induced hyperalgesia 4.2. Chronic …

Chronic stress alters astrocyte morphology in mouse prefrontal cortex

SA Codeluppi, D Chatterjee, TD Prevot… - International Journal …, 2021 - academic.oup.com
Background Neuromorphological changes are consistently reported in the prefrontal cortex
of patients with stress-related disorders and in rodent stress models, but the effects of stress …

Stress and IL-1β contribute to the development of depressive-like behavior following peripheral nerve injury

GJ Norman, K Karelina, N Zhang, JC Walton… - Molecular …, 2010 - nature.com
The physiological link between neuropathic pain and depression remains unknown despite
a high comorbidity between these two disorders. A mouse model of spared nerve injury …