Advances of cobalt nanomaterials as anti-infection agents, drug carriers, and immunomodulators for potential infectious disease treatment

Y Ma, W Lin, Y Ruan, H Lu, S Fan, D Chen, Y Huang… - Pharmaceutics, 2022 - mdpi.com
Infectious diseases remain the most serious public health issue, which requires the
development of more effective strategies for infectious control. As a kind of ultra-trace …

Copper (II) complexes based on thiosemicarbazone ligand: Preparation, crystal structure, Hirshfeld surface, energy framework, antiMycobacterium activity, in silico …

RAC Souza, WRP Costa, EF Faria, MAS Bessa… - Journal of Inorganic …, 2021 - Elsevier
Considering the promising previous results on the remarkable activity exhibited by cobalt (III)
and manganese (II) thiosemicarbazone compounds as antibacterial agents, the present …

Zinc (II) complexes bearing N, N, S ligands: Synthesis, crystal structure, spectroscopic analysis, molecular docking and biological investigations about its antifungal …

RAC Souza, VL Cunha, JH de Souza… - Journal of Inorganic …, 2022 - Elsevier
In the present work, the synthesis, characterization, antifungal activity, molecular docking
study and in silico approach of five thiosemicarbazone derivatives and their corresponding …

Versatile Biological Activities of Thiosemicarbazones and Their Metal Complexes

SB Zahra, A Khan, N Ahmed, M Rafique… - Journal of Molecular …, 2024 - Elsevier
One of the most crucial objectives in medicinal chemistry is the development of innovative
and beneficial bioactive compounds with various biological activities. Thiosemicarbazone …

Metal complexes in diagnosis and therapy

D Tesauro - International Journal of Molecular Sciences, 2022 - mdpi.com
The use of metal complexes for health and healing has been in use for over the last several
millennia and perhaps longer. Transition metals have a long history as antibacterials and …

Insights into the role of the cobalt (III)-thiosemicarbazone complex as a potential inhibitor of the Chikungunya virus nsP4

DOS Martins, RAC Souza, MCLC Freire… - JBIC Journal of …, 2023 - Springer
Chikungunya virus (CHIKV) is the causative agent of chikungunya fever, a disease that can
result in disability. Until now, there is no antiviral treatment against CHIKV, demonstrating …

Antileishmanial and Anti‐Chikungunya Activity of Cu (I)‐N‐Heterocyclic Carbenes

JV Fontes, IA Santos, LB Rosa, RLA Lima… - …, 2022 - Wiley Online Library
Neglected tropical diseases such as Leishmaniasis and Chikungunya fever are worldwide
public health challenges mainly affecting tropical and subtropical countries. One cationic [Cu …

Synthesis, crystal structure, spectroscopic and computational investigations of the newly synthesized Schiff bases scaffold as enzyme inhibitor

MA Raza, U Farwa, A Ashraf, EB Poyraz… - … Acta Part A: Molecular …, 2023 - Elsevier
The current project was planned to access the enzyme inhibition potential of the synthesize
imines;(E)-2-(2-hydroxy-4, 5-dimethoxybenzylideneamino) benzonitrile 1 and (E)-2-(((3 …

[HTML][HTML] In Vitro and In Silico Studies of the Antimicrobial Activity of Prenylated Phenylpropanoids of Green Propolis and Their Derivatives against Oral Bacteria

TM Vieira, JG Barco, SL de Souza, ALO Santos… - Antibiotics, 2024 - mdpi.com
Artepillin C, drupanin, and plicatin B are prenylated phenylpropanoids that naturally occur in
Brazilian green propolis. In this study, these compounds and eleven of their derivatives were …

Metal complexes of thiosemicarbazones derived by 2-quinolones with Cu (I), Cu (II) and Ni (II); Identification by NMR, IR, ESI mass spectra and in silico approach as …

AA Aly, EM Abdallah, SA Ahmed, MM Rabee… - Journal of Molecular …, 2022 - Elsevier
Substituted thiosemicarbazones derived by 2-quinolone were synthesized to investigate
their complexation capability towards Cu (I), Cu (II) and Ni (II) salts. The structure of the …