Parasitic protozoa and helminths are a diverse group of organisms which together form a
major cause of infectious disease in humans and livestock. Studies in animal models have …

Publisher Summary Although there are several reports of Leishmania parasitizing cells other
than macrophages or even existing extracellularly in mammalian tissue, it is generally …

We purified poly (A)+ mRNA from the spleen and lymph nodes at designated times after
infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 …

Functional subsets of human T cells were delineated by analyzing patterns of lymphokines
produced by clones from individuals with leprosy and by T cell clones of known function …

BALB/c mice can be protected against a normally fatal Leishmania major infection by
immunization with a partially purified, soluble subfraction of the parasite (fraction 9). In this …

Leishmaniasis is a parasitic disease transmitted by phlebotomine sand flies. The role of
sand fly saliva in transmission of the disease was investigated by injecting mice with …

Resistant C57BL/6 mice infected with Leishmania major are self-healing, whereas
susceptible BALB/c mice fail to contain cutaneous infection and subsequently undergo fatal …

A host's ability to resist certain pathogens such as Leishmania major can depend upon the
phenotype of T helper (Th) subset that develops. Different murine genetic backgrounds are …

Resistance to Leishmania major in mice is associated with the generation of distinct CD4+
Th subsets, termed TH1 and TH2. To define the factors contributing to the genesis of these …

The expression of interleukin (IL) 2, IL-4, IL-10, and interferon gamma (IFN-gamma) by
lymphocyte subsets was examined during infection of resistant C57BL/6 and susceptible …