Diabetes-associated susceptibility to tuberculosis: contribution of hyperglycemia vs. Dyslipidemia

MD Ngo, S Bartlett, K Ronacher - Microorganisms, 2021 - mdpi.com
Diabetes is a major risk factor for tuberculosis (TB). Diabetes increases the risk of the
progression from latent tuberculosis infection (LTBI) to active pulmonary TB and TB patients …

The association between monocyte subsets and cardiometabolic disorders/cardiovascular disease: a systematic review and meta-analysis

ES Oh, M Na, CJ Rogers - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Background: Monocyte subsets in humans, ie, classical (CM), intermediate (IM), and non-
classical monocytes (NCM), are thought to differentially contribute to the pathogenesis of …

The role of pathogens in diabetes pathogenesis and the potential of immunoproteomics as a diagnostic and prognostic tool

MU Sohail, F Mashood, A Oberbach… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is a group of metabolic diseases marked by hyperglycemia, which
increases the risk of systemic infections. DM patients are at greater risk of hospitalization …

Single-cell analysis of human PBMCs in healthy and type 2 diabetes populations: dysregulated immune networks in type 2 diabetes unveiled through single-cell …

D Gu, J Lim, KY Han, IH Seo, JH Jee, SJ Cho… - Frontiers in …, 2024 - frontiersin.org
Abnormalities in glucose metabolism that precede the onset of type 2 diabetes (T2D)
activate immune cells, leading to elevated inflammatory factors and chronic inflammation …

[HTML][HTML] Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis

F Fondelli, J Willemyns, R Domenech-Garcia… - The Journal of Clinical …, 2024 - jci.org
Multiple sclerosis (MS) is a chronic disease characterized by dysregulated self-reactive
immune responses that damage the neurons' myelin sheath, leading to progressive …

Nuclear receptor coactivator 6 is a critical regulator of NLRP3 inflammasome activation and gouty arthritis

KG Lee, BK Hong, S Lee, N Lee, SW Kim… - Cellular & Molecular …, 2024 - nature.com
Transcriptional coactivators regulate the rate of gene expression in the nucleus. Nuclear
receptor coactivator 6 (NCOA6), a coactivator, has been implicated in embryonic …

[HTML][HTML] Phenotypical evaluation of lymphocytes and monocytes in patients with type 2 diabetes mellitus in Saudi Arabia

M Allahyani, AM Alshalawi, MR Alshalawii… - Saudi Medical …, 2023 - ncbi.nlm.nih.gov
Objectives: To evaluate the levels of total lymphocytes, B-lymphocytes (CD19+), T-
lymphocytes (CD3+), natural killer (NK) cells (CD3-/CD56+), and monocyte subsets in type 2 …

Impact of type 2 diabetes on the capacity of human macrophages infected with Mycobacterium tuberculosis to modulate monocyte differentiation through a bystander …

MA Valtierra‐Alvarado, G Lugo‐Villarino… - Immunology and cell …, 2021 - Wiley Online Library
Type 2 diabetes mellitus (T2D) is a risk factor for the development of tuberculosis (TB)
through mechanisms poorly understood. Monocytes and macrophages are key effector cells …

Bioactive poly (salicylic acid)‐poly (citric acid) scaffolds improve diabetic wound repair via regulating HIF‐1α, Nrf2 and macrophage

C Xie, J Ma, M Luo, Y Wang… - Journal of Biomedical …, 2024 - Wiley Online Library
Diabetic wounds environment is over‐oxidized, over‐inflammatory, leading to difficulties in
regenerating blood vessels, and retardation of healing in diabetic wounds. Therefore …

Prohibitions in the meta-inflammatory response: a review

N Todosenko, K Yurova, M Vulf… - Frontiers in Molecular …, 2024 - frontiersin.org
Prohibitins are the central regulatory element of cellular homeostasis, especially by
modulating the response at different levels: Nucleus, mitochondria and membranes. Their …