Women mount more vigorous antibody-and cell-mediated immune responses following
either infection or vaccination than men. The incidence of most autoimmune diseases is also …

Recurrent Miscarriage is an early pregnancy complication which affects about 1–3% of child-
bearing couples. The mechanisms involved in the occurrence of recurrent miscarriages are …

The natural cytotoxicity receptors NKp46/NCR1, NKp44/NCR2 and NKp30/NCR3 are critical
for natural killer (NK) cell functions. Their genes are transcribed into several splice variants …

The IL-36 subfamily of cytokines has been recently described as part of the IL-1 superfamily.
It comprises three pro-inflammatory agonists (IL-36α, IL-36β, and IL-36γ), their receptor (IL …

Problem Natural killer (NK) cells are the most abundant lymphocyte population at the
maternal–fetal interface. They are suggested to be important during placentation by …

Objective. Caspase-1 is a component of the NALP3 inflammasome, a cytosolic multiprotein
complex that mediates the processing of pro-inflammatory caspases and cytokines. The …

Background A successful pregnancy is a unique and complex immunological state.
Cytokines seem to be crucial for the implementation of a tolerogenic environment at the feto …

OBJECTIVES:: Interleukin-18 (IL-18) is a proinflammatory cytokine with pleiotrophic qualities
and its roles in pregnancy, labor onset and pregnant complications have been proposed …

Problem Dendritic cells (DC)/natural killer (NK) cells interactions in the deciduas of early
human pregnancies were analyzed in vitro. Method of study Phenotype, cytokine expression …

We review recent studies of two cytokines IL-15 and IL-18, showing that they are the critical
cytokines controlling uterine NK cell cytokine production and cytolytic potential. Further, IL …