Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions
MP Lefranc, G Lefranc - Biomedicines, 2020 - mdpi.com
IMGT®, the international ImMunoGeneTics® information system founded in 1989 by Marie-
Paule Lefranc (Université de Montpellier and CNRS), marked the advent of …
Paule Lefranc (Université de Montpellier and CNRS), marked the advent of …
Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses
EL Shrock, RT Timms, T Kula, EL Mena, AP West Jr… - Science, 2023 - science.org
Despite the vast diversity of the antibody repertoire, infected individuals often mount
antibody responses to precisely the same epitopes within antigens. The immunological …
antibody responses to precisely the same epitopes within antigens. The immunological …
Innate immune system and inflammation in Alzheimer's disease: from pathogenesis to treatment
M Serpente, R Bonsi, E Scarpini… - Neuroimmunomodulation, 2014 - karger.com
Immune activation and inflammation, likely triggered by amyloid-beta (Aβ) deposition, play a
remarkable role in the pathogenesis of Alzheimer's disease (AD), which is the most frequent …
remarkable role in the pathogenesis of Alzheimer's disease (AD), which is the most frequent …
Immunoglobulin and T Cell Receptor Genes: IMGT® and the Birth and Rise of Immunoinformatics
MP Lefranc - Frontiers in immunology, 2014 - frontiersin.org
IMGT®, the international ImMunoGeneTics information system® 1,(CNRS and Université
Montpellier 2) is the global reference in immunogenetics and immunoinformatics. By its …
Montpellier 2) is the global reference in immunogenetics and immunoinformatics. By its …
Antibody-based drugs and approaches against amyloid-β species for Alzheimer's disease immunotherapy
J Liu, B Yang, J Ke, W Li, WC Suen - Drugs & aging, 2016 - Springer
Abstract Alzheimer's disease (AD), one of the most devastating diseases for the older
population, has become a major healthcare burden in the increasingly aging society …
population, has become a major healthcare burden in the increasingly aging society …
A generic method for design of oligomer-specific antibodies
K Brännström, M Lindhagen-Persson, AL Gharibyan… - PLoS …, 2014 - journals.plos.org
Antibodies that preferentially and specifically target pathological oligomeric protein and
peptide assemblies, as opposed to their monomeric and amyloid counterparts, provide …
peptide assemblies, as opposed to their monomeric and amyloid counterparts, provide …
IMGT® Homo sapiens IG and TR Loci, Gene Order, CNV and Haplotypes: New Concepts as a Paradigm for Jawed Vertebrates Genome Assemblies
MP Lefranc, G Lefranc - Biomolecules, 2022 - mdpi.com
IMGT®, the international ImMunoGeneTics information system®, created in 1989, by Marie-
Paule Lefranc (Université de Montpellier and CNRS), marked the advent of …
Paule Lefranc (Université de Montpellier and CNRS), marked the advent of …
[HTML][HTML] Immunoglobulins: 25 years of immunoinformatics and IMGT-ONTOLOGY
MP Lefranc - Biomolecules, 2014 - mdpi.com
IMGT®, the international ImMunoGeneTics information system®(CNRS and Montpellier
University) is the global reference in immunogenetics and immunoinformatics. By its creation …
University) is the global reference in immunogenetics and immunoinformatics. By its creation …
Engineered antibody approaches for Alzheimer's disease immunotherapy
R Robert, KL Wark - Archives of biochemistry and biophysics, 2012 - Elsevier
The accumulation of amyloid-β-peptide (Aβ or A-beta) in the brain is considered to be a key
event in the pathogenesis of Alzheimer's disease (AD). Over the last decade, antibody …
event in the pathogenesis of Alzheimer's disease (AD). Over the last decade, antibody …
From IMGT-ONTOLOGY to IMGT/HighVQUEST for NGS immunoglobulin (IG) and T cell receptor (TR) repertoires in autoimmune and infectious diseases
V Giudicelli, P Duroux, A Lavoie, S Aouinti… - … and Infectious Diseases …, 2015 - hal.science
The analysis of adaptive immune repertoires in autoimmune and infectious diseases
represents a fascinating challenge because of the natural huge diversity of the antigen …
represents a fascinating challenge because of the natural huge diversity of the antigen …