Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Naphthoquinones are the most commonly occurring type of quinones in nature. They are a
diverse family of secondary metabolites that occur naturally in plants, lichens and various …

From Eleutherine plicata, naphthoquinones, isoeleutherine, and eleutherol were isolated,
and previous studies have reported the antioxidant activity of these metabolites. The present …

A series of eight substituted bis-2-hydroxy-1, 4-naphthoquinone derivatives was synthesized
through lawsone condensation with various aromatic and aliphatic aldehydes under mild …

Quinones are a group of semi-volatile organic substances, ubiquitous in nature, belonging
to the class of oxygenated polycyclic aromatic hydrocarbons (Oxygenated PAH). These …

Abstract Naphthoquinones and 1, 2, 3-triazoles are structural pharmacophore that is known
to impart several cancer cells. This work shows a synthetic methodology to obtain hybrid …

The aim of this study was to evaluate the antimicrobial activity of lapachol, α-lapachone, β-
lapachone and six antimicrobials (ampicillin, amoxicillin/clavulanic acid, cefoxitin …

This project was carried out to investigate the feasibility of using microemulsions for
transdermal delivery of lapachol. From the screening of surfactants and oils, a range of …

We report herein a straightforward and efficient one-step reaction to prepare new nor-β-
lapachone derivatives tethered with phenylthio groups at position 3 of the furan ring. We …

Side chain homologated derivatives of 2-chloro-3-(n-alkylamino)-1, 4-naphthoquinone {n-
alkyl: pentyl; L-5, hexyl; L-6, heptyl; L-7 and octyl; L-8} have been synthesized and …