In toxicogenetics, an integrative approach including the prediction of phenotype based on
post-mortem genotyping of drug-metabolising enzymes might help explain the cause of …

There are three possible outcomes from drug therapy: the drug performs as intended; the
drug has no effect; or the drug causes an adverse reaction. Variation in drug and …

Copper is a metal that is commonly found in many evidence types, such as weapons, and
household items, that are often retrieved from crime scenes. We used copper and brass …

Tramadol (TR) metabolism is performed by polymorphic enzymes that are influenced by
genetic polymorphisms. Within this scope, the study presented here aimed to describe 41 …

There has been a worldwide substantial increase in accidental opioid-overdose deaths. The
aim of this review, along with preliminary results from our pilot study, is to highlight the use of …

Molecular autopsy is a very important tool in forensic toxicology. However, many
determinants, such as co-medication and physiological parameters, should be considered …

This study aims to investigate the different clinically relevant allele variants (allele
frequencies) of CYP2D6 gene and to determine whether a specific genotype of CYP2D6 …

Predicting metabolizer phenotype (MP) is typically performed using data from a single gene.
Cytochrome p450 family 2 subfamily D polypeptide 6 (CYP2D6) is considered the primary …

With the rapid development of science and technology, artificial intelligence (AI) has become
an important force to promote innovation in all walks of life. In the field of forensic medicine …

Tramadol (TR) is a widely prescribed pain killer because of its relatively safe profile among
opioids. Nevertheless, intoxication can occur and overdose can lead to fatal outcomes …