Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: an in vivo and in silico study

SC D'Cruz, R Jubendradass, M Jayakanthan… - Food and chemical …, 2012 - Elsevier
Bisphenol A (BPA) is a potential endocrine disruptor and testicular toxicant. Recently, we
have reported that exposure to BPA increases plasma insulin and glucose levels and …

[HTML][HTML] Effects of plants and plant products on the testis

SC D'cruz, S Vaithinathan… - Asian Journal of …, 2010 - ncbi.nlm.nih.gov
For centuries, plants and plant-based products have been used as a valuable and safe
natural source of medicines for treating various ailments. The therapeutic potential of most of …

Overview of the Anticancer Potential of the “King of Spices” Piper nigrum and Its Main Constituent Piperine

E Turrini, P Sestili, C Fimognari - Toxins, 2020 - mdpi.com
The main limits of current anticancer therapy are relapses, chemoresistance, and toxic
effects resulting from its poor selectivity towards cancer cells that severely impair a patient's …

Safety aspects of the use of isolated piperine ingested as a bolus

R Ziegenhagen, K Heimberg, A Lampen… - Foods, 2021 - mdpi.com
Piperine is a natural ingredient of Piper nigrum (black pepper) and some other Piper
species. Compared to the use of pepper for food seasoning, piperine is used in food …

[HTML][HTML] The potentiality of medicinal plants as the source of new contraceptive principles in males

IP Ogbuewu, IC Unamba-Oparah… - … American Journal of …, 2011 - ncbi.nlm.nih.gov
Rising human population throughout the world especially in developing and
underdeveloped countries has detrimental effects on life supporting system on earth …

Effect of a 60‐Day Oral Gavage of a Crude Alkaloid Extract From Chromolaena odorata Leaves on Hormonal and Spermatogenic Indices of Male Rats

MT Yakubu - Journal of andrology, 2012 - Wiley Online Library
The present study was aimed at investigating the effects of the crude alkaloids isolated from
Chromolaena odorata leaves on the hormonal and spermatogenic indices of male rats. The …

Diverged effects of piperine on testicular development: Stimulating leydig cell development but inhibiting spermatogenesis in rats

X Chen, F Ge, J Liu, S Bao, Y Chen, D Li, Y Li… - Frontiers in …, 2018 - frontiersin.org
Background: Piperine is the primary pungent alkaloid isolated from the fruit of black
peppercorns. Piperine is used frequently in dietary supplements and traditional medicines …

Oxidative stress induced by piperine leads to apoptosis in Candida albicans

A Thakre, V Jadhav, R Kazi, A Shelar, R Patil… - Medical …, 2021 - academic.oup.com
Candida albicans is a member of pathogens with potential drug resistance threat that needs
novel chemotherapeutic strategies. Considering the multifarious biological activities …