Sickle cell disease (SCD) encompasses an inherited group of disorders with the presence of
hemoglobin S (HbS) as a homozygous mutation (HbSS) or compound heterozygosity with …

Background Sickle cell disease (SCD) is a genetic hemoglobinopathy with an incidence of
250–300,000 births per year worldwide. SCD leads to a diffuse vasculopathy which …

Children with sickle cell disease (SCD) have an increased risk of sleep disordered breathing
(SDB) compared with the general pediatric population. There has been a growing research …

Because of its prevalence and severity, sickle cell disease (SCD) is one of the world's major
public health problems. In Africa, the frequency of carriers of the sickle cell gene is variable …

Adenotonsillectomy is one of the most common surgical procedures performed by
otolaryngologists. It is vital that surgeons are aware of the risks in performing this surgery …

Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy leading to
hemolysis, increased endothelial adhesion, inflammation, and vasculopathy. While most …

This scoping review aimed to determine the safety and efficacy of adenotonsillectomy in
patients with sickle cell disease (SCD) and obstructive sleep apnea (OSA). Six databases …

Youth living with sickle cell disease (SCD) often face neurocognitive challenges, regardless
of accompanying neurological issues. While screening and intervention advancements have …

The pathophysiology of pulmonary hypertension (PH) in sickle cell disease (SCD) is
multifactorial: hemolysis, hypercoagulability, hypoxemia, oxidative stress, platelet activation …