Thirty years after the discovery of its production by activated macrophages, our appreciation
of the diverse roles of nitric oxide (NO) continues to grow. Recent findings have not only …

Brucella is an intracellular bacterium that causes abortion, reproduction failure in livestock
and leads to a debilitating flu-like illness with serious chronic complications if untreated in …

Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …

The immune response is essential to protect organisms from infection and an altered self. An
organism's overall metabolic status is now recognized as an important and long-overlooked …

Brucellosis is a highly prevalent zoonotic disease characterized by abortion and
reproductive dysfunction in pregnant animals. Although the mortality rate of Brucellosis is …

Brucella is a facultative intracellular pathogen that causes zoonotic infection known as
brucellosis which results in abortion and infertility in natural host. Humans, especially in low …

Eradication of persistent intracellular bacterial pathogens with antibiotic therapy is often slow
or incomplete. However, strategies to augment antibiotics are hampered by our poor …

Evasion of host immune responses is a prerequisite for chronic bacterial diseases; however,
the underlying mechanisms are not fully understood. Here, we show that the persistent …

Brucella spp. are facultative intracellular bacterial pathogens responsible for brucellosis, a
worldwide zoonosis that causes abortion in domestic animals and chronic febrile disease …

Many intracellular pathogens exploit host secretory trafficking to support their intracellular
cycle, but knowledge of these pathogenic processes is limited. The bacterium Brucella …