[HTML][HTML] Antiphospholipid Antibodies as Key Players in Systemic Lupus Erythematosus: The Relationship with Cytokines and Immune Dysregulation
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by an
overproduction of cytokines, such as interleukins and interferons, contributing to systemic …
overproduction of cytokines, such as interleukins and interferons, contributing to systemic …
Can transcriptomics guide the management of SLE-associated APS?
JS Knight, MG Tektonidou - Nature Reviews Rheumatology, 2024 - nature.com
The management of antiphospholipid syndrome is hindered by heterogeneous clinical
presentations. Whole-blood transcriptomics have the potential to identify previously …
presentations. Whole-blood transcriptomics have the potential to identify previously …
Neuropsychiatric involvement in systemic lupus erythematosus contributes to organ damage beyond the nervous system: a post-hoc analysis of 5 phase III …
D Nikolopoulos, N Cetrez, J Lindblom… - Rheumatology …, 2024 - Springer
Objective To investigate the association between neuropsychiatric systemic lupus
erythematosus (NPSLE) and SLICC/ACR damage index (SDI) items, especially non …
erythematosus (NPSLE) and SLICC/ACR damage index (SDI) items, especially non …
[HTML][HTML] Identification and experimental validation of diagnostic and prognostic genes CX3CR1, PID1 and PTGDS in sepsis and ARDS using bulk and single-cell …
J Jiang, Y Chen, Y Su, L Zhang, H Qian… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Background Sepsis is an uncontrolled reaction to infection that causes severe organ
dysfunction and is a primary cause of ARDS. Patients suffering both sepsis and ARDS have …
dysfunction and is a primary cause of ARDS. Patients suffering both sepsis and ARDS have …
Kidney whole-transcriptome profiling in primary antiphospholipid syndrome reveals complement, interferons and NETs-related gene expression
Objective Pathogenesis of antiphospholipid syndrome (APS) remains poorly elucidated. We
aimed to evaluate for the first time kidney transcriptome profiles in primary APS vs systemic …
aimed to evaluate for the first time kidney transcriptome profiles in primary APS vs systemic …
Uncovering Immune Surveillance Deficiency in B Cell-Driven Autoimmune Disease
H Shi, H Pan, X Wei, J Qian, S Yu, C Fan, S He, L Li… - 2025 - researchsquare.com
Antiphospholipid syndrome (APS) serves as a prototypical disease model for investigating
immune tolerance breakdown in systemic autoimmunity of B cell. Single-cell RNA and V (D) …
immune tolerance breakdown in systemic autoimmunity of B cell. Single-cell RNA and V (D) …
[PDF][PDF] Uncovering Immune Surveillance Deficiency in B Cell-Driven Autoimmune
H Pan, X Wei, J Qian, S Yu, C Fan, S He, L Li, Z Ding… - assets-eu.researchsquare.com
Antiphospholipid syndrome (APS) serves as a prototypical disease model for investigating
immune tolerance breakdown in systemic autoimmunity of B cell. Single-cell RNA and V (D) …
immune tolerance breakdown in systemic autoimmunity of B cell. Single-cell RNA and V (D) …