Open-label placebo: reflections on a research agenda

TJ Kaptchuk - Perspectives in biology and medicine, 2018 - muse.jhu.edu
Open-label placebos (OLP)—placebo pills honestly prescribed—have challenged the notion
that placebos require either deception or concealment to evoke salubrious benefits. This …

The cognitive neuroscience of placebo effects: concepts, predictions, and physiology

S Geuter, L Koban, TD Wager - Annual review of neuroscience, 2017 - annualreviews.org
Placebos have been used ubiquitously throughout the history of medicine. Expectations and
associative learning processes are important psychological determinants of placebo effects …

Brain systems underlying the affective and social monitoring of actions: an integrative review

L Koban, G Pourtois - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Action monitoring allows the swift detection of conflicts, errors, and the rapid evaluation of
outcomes. These processes are crucial for learning, adaptive behavior, and for the …

What's in a word? How instructions, suggestions, and social information change pain and emotion

L Koban, M Jepma, S Geuter, TD Wager - Neuroscience & Biobehavioral …, 2017 - Elsevier
Instructions, suggestions, and other types of social information can have powerful effects on
pain and emotion. Prominent examples include observational learning, social influence …

Mechanisms and therapeutic implications of the placebo effect in neurological and psychiatric conditions

D Murray, AJ Stoessl - Pharmacology & therapeutics, 2013 - Elsevier
The power of a placebo to effect clinically meaningful neurobiological change comparable to
pharmacological therapies has been demonstrated, although the mechanisms are not fully …

Phase 2b, randomized, double‐blind 12‐week studies of TZP‐102, a ghrelin receptor agonist for diabetic gastroparesis

RW McCallum, A Lembo, T Esfandyari… - …, 2013 - Wiley Online Library
Abstract Background TZP‐102, a potent, oral, ghrelin receptor agonist, improved diabetic
gastroparesis symptoms in Phase 2a. Methods Patients with type 1 or 2 diabetes, delayed …

Frontal-brainstem pathways mediating placebo effects on social rejection

L Koban, E Kross, CW Woo, L Ruzic… - Journal of …, 2017 - Soc Neuroscience
Placebo treatments can strongly affect clinical outcomes, but research on how they shape
other life experiences and emotional well-being is in its infancy. We used fMRI in humans to …

'Why should I care?'Challenging free will attenuates neural reaction to errors

D Rigoni, G Pourtois, M Brass - Social cognitive and affective …, 2015 - academic.oup.com
Whether human beings have free will has been a philosophical question for centuries. The
debate about free will has recently entered the public arena through mass media and …

Inducing expectations for health: effects of verbal suggestion and imagery on pain, itch, and fatigue as indicators of physical sensitivity

KJ Peerdeman, AIM van Laarhoven, ART Donders… - PloS one, 2015 - journals.plos.org
Research into placebo effects has convincingly shown that inducing positive outcome
expectations can reduce pain and other physical sensations. However, the comparative …

Topiramate modulates trigeminal pain processing in thalamo-cortical networks in humans after single dose administration

JM Hebestreit, A May - PLoS One, 2017 - journals.plos.org
Migraine is the sixth most common cause of disability in the world. Preventive migraine
treatment is used to reduce frequency, severity and duration of attacks and therefore lightens …